PURPOSE To investigate the association between Agent Orange (AO) exposure and long-term prostate cancer (PC) outcomes. MATERIAL AND METHODS Data from 1,882 men undergoing radical prostatectomy for PC between 1988 and 2011 at Veterans Affairs Health Care Facilities were analyzed from the Shared Equal Access Regional Cancer Hospital database. Men were stratified by AO exposure (binary). Associa...

PURPOSE Bipolar energy has recently been used for transurethral resection of bladder tumor (TURBT). Although this modality is thought to be safe, there are some controversies concerning the pathologic accuracy of the biopsy specimens. We compared clinical efficacy, safety, and pathologic characteristics of deep biopsy specimens between bipolar and monopolar devices. MATERIALS AND METHODS From...

BACKGROUND AND PURPOSE Although high-resolution MR imaging is a valuable diagnostic tool, in vivo MR imaging has not yet been compared with in vitro MR imaging and histologic techniques following experimental spinal cord injury (SCI). The goal of the present study was to evaluate the feasibility of using in vivo MR imaging, in vitro MR imaging, and histologic techniques to study pathologic chan...

BACKGROUND Patients with frontotemporal dementia due to mutation of progranulin may have a distinct phenotype. OBJECTIVE To identify distinct clinical and pathologic features of patients with frontotemporal dementia who have mutations of progranulin (GRN). DESIGN Retrospective clinical-pathologic study. SETTING Academic medical center. PATIENTS Twenty-eight patients with frontotemporal ...

R.J. Pignolo et al. (eds.), Fractures in the Elderly, Aging Medicine, DOI 10.1007/978-1-60327-467-8_2, © Springer Science+Business Media, LLC 2011 Abstract Pathologic fractures can be caused by any type of bone tumor, but the overwhelming majority of pathologic fractures in the elderly are secondary to metastatic carcinomas. Multiple myeloma is also common in the elderly and has a high incidenc...

PURPOSE To determine the ability of endorectal magnetic resonance imaging (erMRI) and other pretreatment factors to predict the presence and extent of extraprostatic extension (EPE) in men with Gleason score (GS) 7 prostate cancer. METHODS AND MATERIALS We included patients with clinical stage T1c-T2c, GS=7 (3+4 or 4+3), and prostate-specific antigen (PSA) <10ng/mL who underwent pre-prostatec...

PURPOSE The aim of this study was to investigate the prognosis of papillary thyroid carcinoma (PTC) patients according to different pathologic grades of lymphocytic thyroiditis (LT). MATERIALS AND METHODS This study included 144 PTC patients who underwent total thyroidectomy with radioactive iodine remnant ablation therapy. Pathologic grades of LT were separated at two points, chronic lymphoc...