Although children represent 25% of the U.S. population and nearly 40% of the world's population, pediatric product development typically lags behind that targeted at adults. Here the authors describe the challenges and opportunities of pediatric product development and the unique issues that surround pediatric research. Assuring advancement in pediatric health through clinical and translational...

The Nuclear Medicine Global Initiative (NMGI) was formed in 2012 and consists of 13 international organizations with direct involvement in nuclear medicine. The underlying objectives of the NMGI were to promote human health by advancing the field of nuclear medicine and molecular imaging, encourage global collaboration in education, and harmonize procedure guidelines and other policies that ult...

CAM therapies have become increasingly  popular in pediatric populations. phytotherapy are the most common CAM used in children. Yet, little is known about children’s preferences for CAM. But It is expected to become more widely integrated into the modern medical system, including the medical curriculum.The aim of this study is to introduce the prevalence and characteristics of CAM use in Pedia...

OBJECTIVES This report presents estimates on the availability of pediatric services, expertise, and supplies for treating pediatric emergencies in U.S. hospitals. METHODS The Emergency Pediatric Services and Equipment Supplement (EPSES) was a self-administered questionnaire added to the 2002-03 National Hospital Ambulatory Medical Care Survey (NHAMCS). NHAMCS samples non-Federal, short-stay a...

Article Pediatric evaluation of clinical specificity and sensitivity SARS-CoV-2 IgG IgM serology assays was published on May 1, 2021 in the journal Clinical Chemistry Laboratory Medicine (CCLM) (volume 59, issue 6).

Steven and Alexandra Cohen Children’s Medical Center of New York, New Hyde Park, NY; Feinstein Institute for Medical Research, Manhasset, NY; University of Arkansas for Medical Sciences, Little Rock, AR; Dana-Farber Cancer Institute, Boston, MA; Harvard Medical School, Boston, MA; Department of Hematology, Brigham and Women’s Hospital, Boston, MA; Office of the Clinical Director, National Human...

Multicenter clinical research studies are often needed to address issues of generalizability, conditions with low incidence, adequate statistical power, and potential study bias. While pediatric research networks began work in the 1950s, and Rhode Island physicians have contributed to many of these studies, pediatric emergency medicine (PEM) collaboratives are relative newcomers. Since the mid-...

Affiliations: Service de Pneumologie Pédiatrique, Hôpital Trousseau, Assistance Publique Hôpitaux de Paris (APHP), Sorbonne Universités, Université Pierre et Marie Curie (UPMC), Inserm U933, Paris, France. Service de Pneumologie Pédiatrique, Hôpital Universitaire Necker Enfants Malades, APHP, Université Paris Descartes, Paris, France. Service de Pédiatrie, Centre Hospitalier Intercommunal de Cr...

UNLABELLED Universally applied standards for administering radiopharmaceutical doses in children do not presently exist. Hence, pediatric radiopharmaceutical dosimetry varies considerably from institution to institution and is generally based on the recommended adult dose adjusted for body mass. METHODS We surveyed 13 pediatric hospitals in North America to obtain objective data on dosimetry ...

Introduction: Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is a clinically heterogeneous disorder with a number of different etiologies and disease mechanisms. Inflammatory and postinfectious autoimmune presentations of PANS occur frequently, with some clinical series documenting immune abnormalities in 75%–80% of patients. Thus, comprehensive treatment protocols must include immunolo...