Renal monoclonal immunoglobulin deposition disease (MIDD) is a rare defined by of light chains and/or heavy on basement membranes and vascular walls the kidney. We describe case 71-year-old woman with kidney failure secondary to lambda in association plasma cell dyscrasia. Her initial serum protein electrophoresis did not demonstrate protein, classic cast nephropathy was absent renal biopsy. Ho...

BACKGROUND Renal biopsy is not free from complications and patients who undergo this procedure are usually hospitalized to receive intensive care for several days after biopsy. In contrast, after this period, routine follow-up to detect biopsy-associated complications is rarely scheduled, unless the patient develops a clinical manifestation. We describe a case of marked enlargement of arteriove...

I read with great interest the case report by Abourbih and colleagues.1 In few last decades, the diagnosis of small renal masses (SRMs) has increased due to the routine use of imaging modalities.2 Small renal masses represent 48% to 66% of all renal cell carcinomas and only 1% of them will spread to distant metastasis.3 There is a need to biopsy SRMs to distinguish their behavior by radiologic ...

INTRODUCTION A clinical index that discriminates disease progression independent of histopathologic features may be valuable in the best timing of biopsy. OBJECTIVE This study addresses the question if a clinical index based on cortical echogenicity, renal length to body height ratio (KL/H), and serum creatinine levels predicts renal survival. METHODS The study enrolled 154 patients. Biopsy...

INTRODUCTION Data on the efficacy and safety of everolimus in pediatric renal transplantation compared to other immunosuppressive regimens are scarce. PATIENTS/METHODS We therefore performed a multicenter, observational, matched cohort study over 4 years post-transplant in 35 patients on everolimus plus low-dose cyclosporine, who were matched (1:2) with a control group of 70 children receivin...

In milk-alkali syndrome the degree of renal impairment varies greatly. Few reports have been published describing structural changes on renal biopsy. In three illustrative cases, impairment of renal function was related to morphological changes shown on percutaneous biopsy. Milk-alkali syndrome should be considered as a cause of renal dysfunction in patients with a long history of dyspensia.

Small renal masses (SRMs) are defined as radiologically enhancing renal masses of less than 4 cm in maximal diameter. The incidence of renal cell carcinoma (RCC) has increased in recent years, which is mainly due to the rise in incidental detection of localized SRMs. However, the cancer-specific mortality rate is not increasing. This discrepancy may be dependent on the indolent nature of SRMs. ...

Background IgA nephropathy is a primary cause of renal failure, and inflammation and renal fibrosis are the main mechanisms leading to kidney damage. The serum fibrinogen level is closely related to inflammatory states, but its relationship to the prognosis of IgA nephropathy (IgAN) is unclear. Materials and Methods 1053 patients diagnosed with IgAN after renal biopsy were enrolled from two N...

AIMS To determine the role of interstitial myofibroblasts in the progression of membranous nephropathy; and to assess the predictive value of quantifying myofibroblasts in determining long term renal outcome. METHODS All cases of membranous nephropathy, diagnosed by renal biopsy at University Hospital of South Manchester between 1984 and 1987, were studied retrospectively. The biopsy specimen...