Objective: Influenza A virus infections are still a major health problem and the choices available for the control and treatment of the disease are limited. This research evaluated in vitro and in vivo antiviral effects of Peganum harmala L. seeds (PHS) extract against influenza A virus. Materials and Methods: In this research, in vitro anti-influenza A virus activity of the extract was assesse...

Peganum garmala contains in its composition quinazoline (L-peganine (vasicin), pegamine, peganol, deoxypeganine, peganidin, etc.) and β-carboline (harmine, harman, harmaline, harmalol, alkaloids, which also cause different pharmacological activity harmala preparations. The accumulation of alkaloids depends on the stage ontogenesis differs aboveground underground parts plant. aim work is to dete...

Background and Aim Acanthamoeba is one of free-living amoebas, which are very abundant in nature. As a amoeba, this parasite has high lethality, especially people with underlying diseases, so researchers always looking for way to combat it. Drug plants good fight species. In study, we aimed investigate the lethal effect extract Oliveria decumbens vent Peganum harmala alcoholic on Acanthamoeba. ...

Traditionally, Peganum harmala seeds (P.h) have been extensively used in the Asia region. We have previously reported the increase of fear behavior by systemic administration of P.h extract. Here, we evaluated the effect of central administration of the extract on the fear behavior. Method: Methanolic extract of the plant's seeds (37% humidity) was prepared for the investigation. Elevated pl...

Background: ß-carbolines, harmaline and harmine, are the major alkaloids presenting in the seeds of the Peganum harmala L. These alkaloids are known as herbal active principals with potential use in pharmaceutical and medicine. Objectives: To assess the growth inhibitory effect of phyto-alkaloids, harmaline and harmine, on cancer cell lines. Method...