Pelargonium species have various uses in folk medicine as traditional remedies, and several of them have been screened for their biological activity, including anticancer. Pelargonium quercetorum Agnew (P. quercetorum) is traditionally used for its anthelminthic activity. However, little is known about its biological activity or its effect on cancer cells. The aim of the present study was to de...

background: nanosilver particles are among the potentially candidates for modulating the redox status and changing the growth, performance and quality of plants because of their physicochemical characteristics.   objective: this study was carried out to elucidate the potential effects of nanosilver particles application on variations of photosynthetic pigments (chlorophyll and carotenoids) and ...

background staphylococcus aureus is one of the most causative organisms in the skin wound infections. development of resistant s. aureus to current treatments in individuals with low immunity is a global concern. the aim of this study was to evaluate the efficacy of herbal formulation against skin wound infection. methods the efficacy of herbal formulation containing oliveria decumbens and pela...

Premise In semiarid regions, decreasing rainfall presents a challenge to perennial seedlings that must reach sufficient size survive the first year’s seasonal drought. Attaining large storage organ has been hypothesized enhance drought resilience in geophytes, but building larger organs requires faster growth, paradoxically, some traits confer growth are highly sensitive We examined whether tub...

Background Pelargonium sidoides (PS) is an African herbaceous, perennial plant in the geranium family. The root is the medically part used for respiratory problems [1]. The reported pharmacological activities include moderate direct antibacterial and antiviral potencies and immunomodulatory properties. An alcohol extract of PS has become popular in Germany as a treatment for different respirato...

WS79089B a highly specific endothelin converting enzyme (ECE) inhibitor has been isolated from the fermentation broth of Streptosporangium roseum No. 79089. WS79089B showed highly selective ECE inhibition activity with IC50 value of 0.14 microM and behaved as a competitive inhibitor of ECE, with Ki values of 8.9 x 10(-8) M. The sodium salt of WS79089B (FR901533) inhibited big endothelin-1 (big ...

Farnesyl diphosphate (FPP) and all fifteen positional isomers of ((13)C1)FPP were enzymatically converted by the bacterial terpene cyclases corvol ether synthase from Kitasatospora setae, the epi-cubebol synthase from Streptosporangium roseum, and the isodauc-8-en-11-ol synthase from Streptomyces venezuelae. The enzyme products were analysed by GC-MS and GC-QTOF MS(2) and the obtained data were...

The fine structure of the Golgi apparatus during development of tetrasporangia of Callithamnion roseum is described. Dictyosomes and associated vesicles of 4 developmental stages of sporangia are examined. The wall of sporangia exhibits a heretofore unseen cuticle in red algae. Development of the spore wall and a new plasma membrane around spores occurs through fusion of adjacent Golgi vesicles...