نتایج جستجو برای: pepsinogen ii
تعداد نتایج: 581088 فیلتر نتایج به سال:
Potentiometric titrations of pepsinogen as functions of ionic strength and temperature were studied. It was found that the ionic strength has a minor effect on the titration behavior of the protein. The maximum values of the buffering capacity in the pH range of 6.0 to 9.0 were found at pH values corresponding to those at which a conformational change of the protein occurs as determined by opti...
BACKGROUND Despite the high prevalence of gastroesophageal reflux disease (GERD), its risk factors are still a subject of controversy. This is probably due to inadequate distinction between reflux esophagitis (RE) and non-erosive reflux disease (NERD), and is also due to inadequate evaluation of adjacent stomach. Our aim is therefore to define background factors of RE and NERD independently, ba...
Recent case-control studies reported an association between H. pylori infection and Alzheimer's disease (AD). Our aim was to compare cognitive impairment, neuroinflammation, and cerebrovascular lesion load in a group of AD patients according to their H. pylori status. For the 53 AD patients included, we assessed: clinical data (vascular comorbidities and cognitive assessment), biological data (...
A study of the kinetics of the transformation of swine pepsinogen into pepsin under a variety of conditions has been made. The results show that the transformation as a whole is essentially autocatalytic in nature under all conditions. Evidence is presented to show the existence of a compound intermediate between pepsinogen and pepsin. This compound was found to be a reversibly dissociable comp...
Evidence relating to the structure and properties of swine pepsinogen and pepsin has been reviewed and used to suggest a tentative two dimensional picture of the skeleton of these two proteins. When pepsinogen, a folded single peptide chain, is converted to pepsin, there is a profound change in the physical and chemical properties of the protein. In an as yet unknown manner, except that it is i...
Studies have indicated that serum pepsinogen (PG) levels are not only markers for chronic atrophic gastritis but also predictive risk factors for gastric cancer. However, serum PG levels can change because of pathological conditions other than gastritis. We report the first case in which abnormally high serum PG II levels (168.8 ng/mL) led to the discovery of a large tumor covering a wide area ...
BACKGROUND Serum pepsinogen (PG) levels are valuable in the diagnosis of gastric diseases. However, PG levels are affected by many factors such as the area and race. This study aimed to investigate serum PG levels in patients with different gastric diseases who were Chinese Han people in Hunan Province, midsouth China. METHODS A total of 248 gastric disease patients and 34 healthy controls we...
tor for myocardial infarction? Clin Chem 1985;31:585-90. 7. Lindstedt G, Olbe L, Kilander A, et al. Analytical and clinical evaluation of a radioimmunoassay for gastrin. Clin Chem 1985;31:76-82. 8. Krasinski SD, Russell EM, Samloff TM, et al Fundic atrophic gastritis in an elderly population. Effect on hemoglobin and several serum nutritional indicators. J Am Geriatr Soc 1986;34:800-6. 9. Bock ...
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