BackgroundImmune signaling pathways influence neurodevelopment and are hypothesized to contribute the etiology of autism spectrum disorder (ASD). We aimed assess risk ASD in relation levels neonatal acute phase proteins (APPs), key components innate immune function, measured dried blood spots.MethodsWe included 924 cases, 1092 unaffected population-based controls, 203 siblings cases this case-c...

abstract introduction: low self–esteem has a continuous relation with chronic psychiatric disorder. occupational therapy increases self- esteem by performing purposive activities and profoundly believes in the relation of occupation and health .this research, examines the effect of day center of occupation therapy services on patients´ self–esteem and the length of duration of hospitalization i...

CONTEXT Childbirth has an important influence on the onset and course of bipolar affective disorder, and it is well established that there may be a delay of many years before receiving a diagnosis of bipolar disorder following an initial episode of psychiatric illness. OBJECTIVE To study to what extent psychiatric disorders with postpartum onset are early manifestations of an underlying bipol...

Background Findings from family and twin studies suggest that genetic contributions to psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to identify specifi c variants underlying genetic eff ects shared between the fi ve disorders in the Psychiatric Genomics Consortium: autism spectrum disorder, attention defi cit-hyperactivity disorder, bipolar disorder, ...

Background Findings from family and twin studies suggest that genetic contributions to psychiatric disorders do not in all cases map to present diagnostic categories. We aimed to identify specifi c variants underlying genetic eff ects shared between the fi ve disorders in the Psychiatric Genomics Consortium: autism spectrum disorder, attention defi cit-hyperactivity disorder, bipolar disorder, ...