We report a patient with severe chronic periodontitis requiring regenerative periodontal surgery and different types of prosthesis in the maxillary and mandibular regions. The patient was a 57-year-old woman who presented with the chief complaint of occlusal pain. An initial clinical examination revealed that 73% of sites had a probing depth of ≥4 mm, and 60% of sites exhibiting bleeding on pro...

The association between diabetes mellitus and periodontitis has long been discussed with conflicting conclusions. Both of these diseases have a relatively high incidence globally in the general population with a number of common pathways in their pathogenesis. Diabetis mellitus and Periodontitis are polygenic disorders with some degree of immuno-regulatory dysfunction. Numerous reports indicate...

PURPOSE The purpose of this study was to evaluate the effect of a comprehensive preventive program, based on mechanical plaque control and local and systemic antibacterial measures, on periodontal health and preservation of permanent teeth in patients with Papillon-Lefèvre syndrome (PLS). METHODS Thirty-five consecutive PLS patients (median age=7 years; range=3-19 years) were treated and foll...

Periodontal disease is known as the sixth complication of diabetes. Recently, many clinical and epidemiologic reports have shown that local periodontal inflammation induces systemic micro-inflammation, contributing to insulin resistance and increasing the risk of cardiovascular diseases. We have used in vitro and in vivo studies to address the amplification mechanism of periodontal inflammation...

Protease-activated receptor 2 (PAR2) is implicated in the pathogenesis of chronic inflammatory diseases, including periodontitis; it can be activated by gingipain and produced by Porphyromonas gingivalis and by neutrophil protease 3 (P3). PAR2 activation plays a relevant role in inflammatory processes by inducing the release of important inflammatory mediators associated with periodontal breakd...

Periodontal treatment aims at restoring a micro biota compatible with periodontal health. Scaling and root planing can be classified as 'THE GOLD STANDARD” of periodontal care and has been demonstrated to be successful in order to maintain periodontal health for more than 20 years. Whereas periodontal antibiotic therapy aims to reinforce mechanical periodontal treatment and to support host defe...

Background: Bone grafts are widely used in the treatment of periodontal osseous defects. However, many are unfamiliar with their preparation, exact mechanism of action and processing as well as their use as safe and effective graft materials in periodontal therapy. Also, the clinical benefits of this therapeutic practice require further clarification through a proper review. Aim: The purpose of...

The aim of this study was to investigate, by means of histological and histomorphometric analysis, the effects of 24% ethylenediaminetetraacetic acid (EDTA) gel in periodontal tissue when used in combination with conventional periodontal treatment. Periodontitis was induced in the 2nd upper left permanent molars of 45 male Wistar rats by means of ligature. After 5 weeks, this was removed and de...

Periodontal disease is among the most common oral conditions. However, due to absence of patient complaints in cases, dental clinicians often pay less attention periodontal status. This study aimed assess clinicians’ therapy treatment planning patients presenting clinics Isfahan city during 2016-2017. cross-sectional evaluated 251 Isfahan. The plan suggest

PURPOSE The aim of this clinical trial was to explore the impact of intentional passive eruption (IPE) using occlusal reduction on the periodontal parameters of teeth with moderate chronic periodontitis and traumatic occlusion. METHODS This study was performed on 40 teeth from 16 subjects. At baseline, 4 weeks after initial periodontal treatment, and 6 months after IPE, clinical and radiograp...