Peripheral nervous system owns the ability of self-regeneration, mainly in its regenerative microenvironment including vascular network reconstruction. More recently, more attentions have been given to the close relationship between tissue regeneration and angiogenesis. To explore the overlap of molecular mechanisms and key regulation molecules between peripheral nerve regeneration and angiogen...

Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0.001% in general population and 0.16% in patients with neurofibromatosis I (NF I). We report a case of 60 year female presenting with progressive cough and breathlessne...

  Objective (s): Scar formation in injured peripheral nerve bed causes several consequences which impede the process of nerve regeneration. Several animal models are used for scar induction in preclinical studies which target prevention and/or suppression of perineural scar. This study evaluates the translational capacity of four of physical injury models to induce scar formation aro...

Nerve injuries occur by a variety of mechanisms, including traumatic wounds, thermal or chemical damage, myelin or axonal degeneration, and acute compression. These injuries typically result in the loss of motor function, sensory function, or both. Functional recovery is regained upon complete axonal regeneration, which includes remyelination and reinnervation (i.e., synapse formation) of the a...

1Department of Anaesthesiology and Intensive Care Medicine, Semmelweis University, Kutvolgyi ut 4, 1125 Budapest, Hungary 2Department of Anaesthesia and Intensive Care Medicine, Lapeyronie Hospital, Montpellier, France 3Department of Anesthesiology and Pain Medicine, Western Memorial Regional Hospital, 1 Brookfield Avenue, Corner Brook, NL, Canada A2H 6J7 4Department of Anaesthesia and Intensiv...

background: considering the common origin of skin and peripheral nervous system, a tube of dermal layer of skin hypothetically can be an ideal conduit for nerve reconstruction. an experimental study performed to evaluate the nerve regeneration of efficacy into a dermal tube. methods: sixty male wistar rats were used. a 10 mm gap was produced in right sciatic nerves. in group a the autogenous ne...