The Epidermal Growth Factor Receptor (EGFR) is centrally involved in the regulation of key processes of the epithelia, including cell proliferation, survival, differentiation, and also tumorigenesis. Humanized antibodies and small-molecule inhibitors targeting EGFR were developed to disrupt these functions in cancer cells and are currently used in the treatment of diverse metastatic epithelial ...

introduction: the aims of this study were i) to define the chemical constituents of cuminum cyminum (cumin) essential oil, ii) to compare the antimicrobial activity of this oil to that of chlorhexidine (chx) and co-trimoxazole on planktonic and biofilm forms of bacteria isolated from the teeth with persistent endodontic infection and iii ) to compare the cytotoxicity of these medicaments on l92...

Cyanobacteria are found globally due to their adaptation to various environments. The occurrence of cyanobacterial blooms is not a new phenomenon. The bloom-forming and toxin-producing species have been a persistent nuisance all over the world over the last decades. Evidence suggests that this trend might be attributed to a complex interplay of direct and indirect anthropogenic influences. To c...

AIM To prevent possible chronic kidney diseases in healthy school- age children by screening for hematuria and proteinuria using a urine strip. METHODS The incidence of hematuria and proteinuria was determined in 1848 healthy school-age children aged 7 to 14 years by urine screening in the eastern region of Turkey in 2008. Cases with persistent hematuria and/or proteinuria were referred to a ...

The magnetar SGR 1935+2154 is reported to have an anti-glitch, accompanied by fast radio bursts, and transient pulsed emission. In the wind braking model, this triplet event tells people that (1) does not a strong particle can be approximated magnetic dipole in persistent state; (2) Its anti-glitch due enhanced wind, similar first magnetars; (3) emission may decreasing beam during outburst; (4)...

occult hbv infection of hemodialysis (hd) patients is informative in terms of virus transmission. it may be of clinical importance in hd patients. the aim of this study was to investigate the prevalence of anti-hbc in the hd patients. number of 126 patients undergoing hemodialysis were included in this study from main hemodialysis units in yazd. hepatitis b surface antigens (hbsag), hepatitis b...

We appreciate the Letter to the Editor by Drs. Park and Shin regarding our recentmanuscript describing a case of reversible Henoch–Schönlein purpura (HSP) complicating adalimumab (ADA) therapy. We are thankful for their attention to our work and for the interesting arguments raised for our consideration. In the face of such uncertainty in the pathogenesis of HSP related to anti-TNFα therapy (pa...

BACKGROUND Neural stem and progenitor cells of the Enteric Nervous System (ENS) are regarded as a novel cell source for applications in regenerative medicine. However, improvements to the current ENS cell culture protocols will be necessary to generate clinically useful cell numbers under defined culture conditions. Beneficial effects of physiologically low oxygen concentrations and/or the addi...

Phage therapy has been proven to be more effective, in some cases, than conventional antibiotics, especially regarding multidrug-resistant biofilm infections. The objective here was to isolate an anti-Enterococcus faecalis bacteriophage and to evaluate its efficacy against planktonic and biofilm cultures. E. faecalis is an important pathogen found in many infections, including endocarditis and ...