BACKGROUND Bleomycin (B) is an antineoplastic drug that has pulmonary fibrosis as a side effect. There are few experimental studies about the effects of physical therapy treatment in this case. OBJECTIVE The objective was to study rat lungs treated with B and precocious intervention by transcutaneous electrical diaphragmatic stimulation (TEDS). METHOD Wistar rats were divided into 4 groups ...

BACKGROUND Storage of canine packed red blood cells (pRBCs) can increase erythrocyte phosphatidylserine (PS) expression and eicosanoid concentrations. HYPOTHESIS/OBJECTIVES To determine the effects of leukoreduction on erythrocyte PS expression and eicosanoid concentrations in stored units of canine pRBCs. Our hypothesis was that leukoreduction would decrease PS expression and eicosanoid conc...

Glucocorticoids (GCs) have been widely applied to treat patients with chronic obstructive pulmonary disease (COPD). But the effect of GCs was not ideal. This study was to observe whether erythromycin could enhance the anti-inflammatory activity of budesonide in COPD model rats and to explore the mechanism involved. In this study, male Sprague-Dawley rats were divided into five groups: healthy c...

AIMS Chewing of betel quid (BQ) increases the risk of oral cancer and oral submucous fibrosis (OSF), possibly by BQ-induced toxicity and induction of inflammatory response in oral mucosa. METHODS Primary gingival keratinocytes (GK cells) were exposed to areca nut (AN) components with/without inhibitors. Cytotoxicity was measured by 3-(4,5-dimethyl- thiazol- 2-yl)-2,5-diphenyl-tetrazolium brom...

Abstract One of the biotechnology reproductive used is estrus synchronization. This study determined body’s physiological, estradiol level, and ovarian follicle diameter in Peranakan Ongole (PO) cow synchronization using modified progesterone-PGF2α double injection PGF2α. 10 PO cows which were divided into two groups. Group 1, given a intravaginal sponge containing 250 mg progesterone/sponge fo...

Prostanoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Receptors [701]) are activated endogenous ligands prostaglandins PGD2, PGE1, PGE2 , PGF2α, PGH2, prostacyclin [PGI2] and thromboxane A2. Differences similarities between human rodent prostanoid receptor orthologues, their specific roles in pathophysiologic conditions reviewed [452]. Measurement of potency PGI2 A2 is h...

Prostanoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Receptors [694]) are activated endogenous ligands prostaglandins PGD2, PGE1, PGE2 , PGF2α, PGH2, prostacyclin [PGI2] and thromboxane A2. Differences similarities between human rodent prostanoid receptor orthologues, their specific roles in pathophysiologic conditions reviewed [448]. Measurement of potency PGI2 A2 is h...

Embryonic mortality after embryo transfer causes substantial economic losses in the cattle industry. This has been related to the inability of the corpus luteum (CL) to secrete enough progesterone (P4) to prepare the endometrium for embryo implantation and maintain pregnancy. Thus, the objective of this experiment was to evaluate the effects of treatments that induce ovulation of a persistent f...