نتایج جستجو برای: phagocyte disorders
تعداد نتایج: 673312 فیلتر نتایج به سال:
Background: A high percentage of the patients referred to dermatologic clinics are either suffer from self inflicted disorders or from misinterpretation about their own health and organ integrity and or may suffer from different skin sensations including itching, pain, and burning; all of which may develop as a result of their underlying psychopathologies. Objective: Identification of underlyin...
ononuclear phagocytes can fuse to form osteoclasts or multinuclear giant cells. The latter are hallmarks of Crohn’s disease, granulomas, tumors, and fungal and HIV infections. Though the precise function of these syncytia remains unclear, Takeda et al. (page 945) now provide important new insights into phagocyte fusion, suggesting that the process may differ considerably from other types of cel...
The development of a severe invasive bacterial infection in an otherwise healthy individual is one of the most striking and fascinating aspects of human medicine. A small cadre of gram-positive pathogens of the genera Streptococcus and Staphylococcus stand out for their unique invasive disease potential and sophisticated ability to counteract the multifaceted components of human innate defense....
Photobacterium damselae subsp. piscicida (Phdp) is a Gram-negative pathogen agent of an important fish septicemia. The key virulence factor of Phdp is the plasmid-encoded exotoxin AIP56, which is secreted by exponentially growing pathogenic strains. AIP56 has 520 amino acids including an N-terminal cleavable signal peptide of 23 amino acid residues, two cysteine residues and a zinc-binding regi...
Alarmins MRP8 and MRP14 induce stress tolerance in phagocytes under sterile inflammatory conditions.
Hyporesponsiveness by phagocytes is a well-known phenomenon in sepsis that is frequently induced by low-dose endotoxin stimulation of Toll-like receptor 4 (TLR4) but can also be found under sterile inflammatory conditions. We now demonstrate that the endogenous alarmins MRP8 and MRP14 induce phagocyte hyporesponsiveness via chromatin modifications in a TLR4-dependent manner that results in enha...
Chronic granulomatous disease (CGD) is caused by a congenital defect in phagocyte reduced nicotinamide dinucleotide phosphate (NADPH) oxidase production of superoxide and related species. It is characterized by recurrent life-threatening bacterial and fungal infections and tissue granuloma formation. We have created a mouse model of CGD by targeted disruption of p47phox, one of the genes in whi...
ononuclear phagocytes can fuse to form osteoclasts or multinuclear giant cells. The latter are hallmarks of Crohn’s disease, granulomas, tumors, and fungal and HIV infections. Though the precise function of these syncytia remains unclear, Takeda et al. (page 945) now provide important new insights into phagocyte fusion, suggesting that the process may differ considerably from other types of cel...
Chronic granulomatous disease (CGD) is caused by a congenital defect in phagocyte reduced nicotinamide dinucleotide phosphate (NADPH) oxidase production of superoxide and related species. It is characterized by recurrent life-threatening bacterial and fungal infections and tissue granuloma formation. We have created a mouse model of CGD by targeted disruption of p47p h~ one of the genes in whic...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید