familial adenomatous polyposis (fap) is responsible for < 1% of colorectal cancer (crc) cases and is inherited as an autosomal dominant trait. patients generally present hundreds to thousands of adenomas and develop colorectal cancer by age 35- 40 if left untreated. here we report four patients with germline frameshift mutation (small deletion) at exon 15 of adenomatous polyposis coli (apc) tum...

The present monograph studies the asymptotic behaviour of eigenvalues, products and functions of block Toeplitz matrices generated by the Fourier coefficients of a continuous matrix-valued function. This study is based on the concept of asymptotically equivalent sequences of non-square matrices. The asymptotic results on block Toeplitz matrices obtained are applied to vector asymptotically wide...

objective(s) pseudomonas aeruginosa is the most important cause of chronic lung infections and death in patients with cystic fibrosis. determining the distribution of specific strains within patient populations is important in order to examine the epidemiology of the disease and the possibility of cross infection among patients. materials and methods forty six iranian patients with cystic fibro...

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Uncovering DNA sequence variations that correlate with phenotypic changes, e.g., diseases, is the aim of sequence variation studies. Common types sequence variations are Single nucleotide polymorphism (SNP, pronounced snip).SNPs are the third-generation molecular marker. SNP represents a DNA sequence variant of a single base pair with the minor allele occurring in more than 1% of a given popula...