Kinetic resolution of a series fluorinated styrene oxide derivatives was studied using halohydrin dehalogenase. A mutant HheC-W249P catalysed nucleophilic ring-opening with azide and cyanide ions excellent enantioselectivity (E-values up to >200), which gives access various enantiopure ?-substituted alcohols epoxides. It found that the enzyme tolerates substrates in concentrations over 50 mM. H...

Abstract Here, we present a thorough structural study of small, easily accessible amino−organolithium compounds with bridging phenyl and naphthyl moieties. Their crystal structures most likely represent their aggregation as tetramers dimers in both hydrocarbon ethereal solvents. These were further used to generate corresponding aluminium model system. are reported too. All discussed focus on th...

The mol-ecule of title compound, C(13)H(11)N(5), is essentially planar (r.m.s. deviation = 0.0440 Å) and an intra-molecular C-H⋯N hydrogen bond generates an S(6) motif. In the crystal, mol-ecules are connected into chains by inter-molecular N-H⋯N and C-H⋯N hydrogen bonds. In addition, π-π stacking inter-actions are observed between the pyrazole and pyridazine rings [inter-planar distance = 3.68...

The chemistry of frustrated Lewis pairs derived from N-heterocyclic carbenes and a number of Lewis acids has been probed. The combination of 1,3-bis[2,6-(di-iso-propyl)phenyl]-1,3-imidazol-2-ylidene (IDipp) (1) with B(C6F5)3 was shown to give the classical Lewis acid-base adduct (IDipp)B(C6F5)3 (2) which was unreactive. In contrast, the combination 1,3-di-tert-butyl-1,3-imidazol-2-ylidene (3) w...

The title compound, (C(6)H(21)N(4))[TiF(6)]F, was synthesized by the reaction of TiO(2), tris-(2-amino-ethyl)amine, HF and ethanol at 463 K in a microwave oven. The crystal structure consists of two crystallographically independent [TiF(6)](2-) anions, two fluoride anions and two triply-protonated tris-(2-amino-ethyl)-amine cations. The Ti atoms are coordinated by six F atoms within slightly di...

The asymmetric unit of the title polymeric compound, [Li(2)(C(16)H(11)N(2)O(2))(2)(C(16)H(12)N(2)O(2))(2)(CH(3)CH(2)OH)(2)](n), contains two Li(I) ions, two 3-(1-phenyl-1H-pyrazol-3-yl)benzoate ions, two 3-(1-phenyl-1H-pyrazol-3-yl)benzoic acid mol-ecules and two ethanol mol-ecules. In the crystal structure, each of the two Li(I) ions has a distorted tetra-hedral geometry, coordinated by two ca...

Two novel optical power limiters, 2-[ethyl-(4-phenylazo-phenyl)-amino]-ethanol (E4PA) and 2-[ethyl-(4-trifluoromethyl-phenylazo-phenyl)-amino]-ethanol (E4TPA) were synthesized using a diazotization reaction. The purified azo material was made into thin films in a poly(methyl methacrylate) matrix using a gravity settling technique. The electronic nonlinearities of these films were investigated u...

A simple highly versatile and efficient sonochemical synthesis of 1,2,4,5-tetrasubstituted and 2,4,5-trisubstituted imidazoles is achieved by condensation of 1,2-dicarbonyl compound, aldehyde, ammonium acetate and primary amine using antimony trichloride immobilized on silica gel (SiO2-OSbCl2) as a catalyst in ethanol at moderate temperature. Operational simplicity, practicability and applicabi...