Search for pancreatic lipase (PL) inhibitors is essential obesity and associated chronic disease therapy. PL significantly reduce enzyme activity prevent the absorption hydrolysis of triglycerides into free fatty acids. This study provides new evidence screening inhibitory 15 endophytic fungi from 6 medicinal plants in Uzbekistan. In general, extracts almost all twelve endophytes exposed potent...

Phlebotomus riouxi Depaquit, Killick-Kendrick & Léger 1998 was described as a species closely related to Phlebotomus chabaudi Croset, Abonnenc & Rioux 1970, differing mainly by the size and number of setae of the coxite basal lobe. Molecular studies carried out on several populations from Algeria and Tunisia and based on mitochondrial genes cytochrome b (Cytb) and cytochrome oxidase I (COI) sup...

one hundred sera from children 1 - 6 years of age, representative of a large serum collection, were tested for the prevalence of antibodies against different viruses. hemagglutination-inhibition (hi) antibodies were found in 68% for measles; 61 % for rubella; 75'% for influenza a2/hong kong/68, 16% for influenza b/md./59, 0% for group a arboviruses, 10% for group b arboviruses, 3% for phlebotom...

background: cutaneous leishmaniasis is a major health problem in iran in spite of implementation of control pro­gram. this infectious disease caused morbidity in less than 27000 people in 2010. this study was set to determine some ecological aspects of sand flies in fasa district, fars province, southern iran during 2011–2012. methods: a total of 4792 sand flies were captured by means of sticky...

The evolutionary relationships of sand flies and Leishmania are discussed in this report, which draws distinctions between co-association, co-evolution and co-speciation (or co-cladogenesis). Examples focus on Phlebotomus vectors of Le. infantum and Le. major in the Mediterranean subregion.

Visceral Leishmaniasis (VL) is a major health problem in Bihar, India. The disease is caused by a protozoan parasite Leishmania donovani and transmitted by the established vector Phlebotomus argentipes (Diptera: Psychodidae) in India. P. argentipes transmits viral and bacterial pathogens. Nematodes were isolated from the body of P. argentpes for the first time in India. Its role as pathogen is ...

KEY CLINICAL MESSAGE We report a case of a 5-year-old female, resident of Afghanistan, who presented with fever and massive splenomegaly. Bone marrow revealed Leishmania donovani bodies (LD bodies) in macrophages characterized by a kinetoplast and characteristic double dot appearance. She was diagnosed as visceral leishmaniasis which is transmitted by sandflies (Phlebotomus).

Leishmania (L.) infantum is the causative agent in an endemic focus of canine leishmaniasis in the Mont-Rolland district (Thiès, Senegal). In this area, the transmission cycle is well established and more than 30% of dogs and 20% of humans are seropositive for L. infantum. However, the sand fly species involved in L. infantum transmission cycle are still unknown. Between 2007 and 2010, 3654 san...