In the first part the properties of normal mammalian sphingomyelinases are reviewed: The lysosomal acid sphingomyelinase is a polymeric glycoprotein (subunit Mr between 28 000 and 70 000) which hydrolyses natural sphingomyelin, coloured and fluorescent semi-synthetic analogues (trinitrophenyl-aminolauryl-sphingomyelin and pyrenedecanoyl-sphingomyelin) and the synthetic analogue 2-N-hexadecanoyl...

ing examples are Mitchell and Keen in neurosurgery. The average army surgeon was sent back to civilian practice a better surgeon, with an increased respect for cleanliness and ventilation of the sick-room. Women who "nursed" the wounded began to feel the need for professional training. But these were advances within the individual and not within the body of medicine as a whole. Dr. Adams has do...