نتایج جستجو برای: pick c

تعداد نتایج: 1066027  

Journal: :Human molecular genetics 2003
Titta S Blom Matts D Linder Karen Snow Helena Pihko Michael W Hess Eija Jokitalo Ville Veckman Ann-Christine Syvänen Elina Ikonen

Niemann-Pick type C (NPC) disease is a fatal recessively inherited lysosomal cholesterol-sphingolipidosis. Mutations in the NPC1 gene cause approximately 95% of the cases, the rest being caused by NPC2 mutations. Here the molecular basis of a severe infantile form of the disease was dissected. The level of NPC1 protein in the patient fibroblasts was similar to that in control cells. However, th...

1998
ALEXANDER KHEIFETS

is positive semidefinite for every choice of an integer n and of n points z1, . . . , zn ∈ D. The significance of this characterization for interpolation theory is that it gives the necessity part in the Nevanlinna-Pick interpolation theorem: given points z1, . . . , zn ∈ D and w1, . . . , wn ∈ C, there exists w ∈ S with w(zj) = wj for j = 1, . . . , n if and only if the associated Pick matrix ...

2001
Dario Fasino Vadim Olshevsky VADIM OLSHEVSKY

Let P be a symmetric positive definite Pick matrix of order n. The following facts will be proven here: (a) P is the Gram matrix of a set of rational functions, with respect to a inner product defined in terms of a “generating function” associated to P ; (b) Its condition number is lower-bounded by a function growing exponentially in n; (c) P can be effectively preconditioned by the Pick matrix...

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