Laugier-Hunziker syndrome is characterized by idiopathic mucocutaneous pigmentation that may be associated with longitudinal melanonychia. The significance of this condition is due to its inclusion in differential diagnoses of pigmentary disorders of the oral mucosa, especially Peutz-Jeghers syndrome.

We describe a case of an increasing pigmentary plaque on the posterior surface of the lens during follow-up of a case of pigment dispersion syndrome and suggest that this is a new sign of pigment dispersion.

PURPOSE To evaluate the change in ocular function by eye in patients with unilateral pigmentary retinopathy. METHODS Longitudinal regression was used to estimate mean exponential rates of change in Goldmann visual field area (V4e white test light) and in full-field electroretinogram (ERG) amplitudes to 0.5- and 30-Hz white flashes in 15 patients with unilateral pigmentary retinopathy. Snellen...

PURPOSE To estimate the prevalence of early and late age-related macular degeneration (AMD) in India. METHODS Of 7518 people aged 60 years and older identified from randomly sampled villages in North and South India, 5853 (78%) attended an eye examination including fundus photography. Fundus images were graded according to the Wisconsin Age-Related Maculopathy Grading System. RESULTS Fundus...

Systemic elastorrhexis is a widespread hereditary degeneration of mesodermal tissues affecting many structures in the body, particularly the dermis, the media of the arteries, and Bruch's membrane in the eye. Pseudoxanthoma elasticum is one form of elastorrhexis mainly affecting the skin. Degeneration of the elastic lamina of Bruch's membrane results in the formation of angioid streaks in the r...

Systemic elastorrhexis is a widespread hereditary degeneration of mesodermal tissues affecting many structures in the body, particularly the dermis, the media of the arteries, and Bruch's membrane in the eye. Pseudoxanthoma elasticum is one form of elastorrhexis mainly affecting the skin. Degeneration of the elastic lamina of Bruch's membrane results in the formation of angioid streaks in the r...

OBJECTIVES To investigate the prevalence of myocilin (MYOC) mutations in Italian families with glaucoma and to determine the relationship of these mutations to primary open-angle glaucoma (POAG), juvenile open-angle glaucoma (JOAG), and pigmentary dispersion glaucoma. METHODS Twenty-six patients with POAG were selected based on a positive family history of glaucoma. All patients and 210 relat...

The pathogenesis of vitiligo was examined for clues to the pigmentary changes that may occur after treatment with topical imiquimod. The literature varies on the pigmentary changes induced by topical use of imiquimod. The US Food and Drugs Administration lists 68 reports of pigmentary changes out of a total of 1257 reports related to imiquimod lodged from 1997 to 2003. Some studies describe vit...

Abstract Sex differences in ornamentation are common and, species with conventional sex roles, generally thought of as stable, due to stronger sexual selection on males. Yet, especially gregarious species, ornaments can also have non-sexual social functions, raising the possibility that observed plastic. For example, females may invest costly more plastically, protect body and reproductive abil...

cutaneous vascular and pigmentary lesions. The pregnancy of his mother and family history were unremarkable. Physical examination showed bilateral nevus flammeus involving the scalp, face, neck, trunk, upper part of the back, scrotum and the flexor sides of arms and thighs. Large, bluish-grey pigmentation was observed on the abdominal area, back, buttocks, legs and the extensor sides of the arm...