Birth is associated with significant changes in the hypothalamic-pituitarythyroid axis and these changes complicate the proper assessment of thyroid function in neonates. Normal values forT4 (thyroxine) and TSH (thyroid stimulating hormone) in cord blood are not well established. The present study was carried out on 4000 specimens of cord sera of both sexes in order to establish reliable re...

abstract   objective: to evaluate and review our experience with pediatric spinal injuries and factors affecting outcome, the authors conducted a retrospective clinical study of 43 cases (32 boys, 11 girls) of pediatric spine injuries treated during four years (january 1999 to december 2003).   methods: forty-three children with spinal injuries were studied retrospectively over four years and w...

objective oxygen intoxication plays an important role in the pathogenesis of some fetal diseases such as encephalopathy, ischemia& hypoxia. antioxidants can reduce oxidative damage in newborns. the object of this research was measuring total value of antioxidant and vitamin c in blood sample of pregnant women before delivery, and also in umbilical cord blood of their newborn, and repeating thes...

a b s t r a c tintroduction: because of more exposure to mercury compounds, the prenatal and postnatal neurotoxic effects of mercury compounds have gained more attention in last decade. the aim of this study was to investigate the effects of mercuric chloride intoxication on spinal cord development during prenatal period. methods: 36 adult sprague-dawley rats after observing vaginal mating plaq...

the overall goal of this study was to identify the appropriate biomaterials able to facilitate the regeneration in rat's injured adult spinal cord. acute damage to axons is manifested as a breach in their membranes, ionexchange distortion across the compromised region, local depolarization and even conduction block. it would be of particular importance to interrupt the progress of events h...

background: spinal cord injury (sci) occurs most often to young men at the peak of their reproductive health. only 10% of sci men can father children without medical assistance due to potential impairments in ejaculation and sperm quality. objective: the main objective of this experimental study was to evaluate the epididymal necrospermia- sperm death, after chronic sci in rat. materials and me...

background: brain hypoxia-ischemia is a human neonatal injury that is considered a candidate for stem cell therapy. methods: the possible therapeutic potential of human umbilical cord blood (hucb) stem cells was evaluated in 14-day-old rats subjected to the right common carotid occlusion, a model of neonatal brain hypoxia-ischemia. seven days after hypoxia-ischemia, rats received either saline ...

background: spinal cord injury (sci) stimulates an inflammatory reaction that causes substantial secondary damage inside the injured spinal tissue. the purpose of this study was to determine the anti-inflammatory effects of epigallocatechin gallate (egcg) on traumatized spinal cord. methods: rats were randomly divided into four groups of 12 rats each as follow: sham-operated group, trauma group...

spinal cord injury (sci) leads to a significant health problem associated with a broad range of secondary complications and disabilities. in this regard, animal models can help us to understand the pathobiology of sci and evaluate the effects of potential treatments for sci. in contusion models of sci, different devices including surgical spring-loaded clips, balloons, forceps, weights and the ...