BACKGROUND A mechanical noxious stimulator is useful for studies of pain, both for clinic and basic research. We propose to use a pinch stimulator that can not only generate a quantitative, reproducible noxious pinch but also simultaneously provide a synchronous external trigger signal, which is essential for acquisition of evoked potentials. METHODS For ethical considerations, audible and vi...

The primary purpose of this study was to establish clinical norms for adults aged 20 to 75+ years on four tests of hand strength. A dynamometer was used to measure grip strength and a pinch gauge to measure tip, key, and palmar pinch. A sample of 310 male and 328 female adults, ages 20 to 94, from the seven-county Milwaukee area were tested using standardized positioning and instructions. Right...

BACKGROUND Hand strength is an important independent surrogate parameter to assess outcome and risk of morbidity and mortality. This study aimed to determine the predictive power of cofactors and to predict population-based normative grip and pinch strength. METHODS A representative population survey was used as the basis for prediction analyses (n = 978). Bivariate relationships between grip...

In order to effectively solve the risk of safety on power window, an improved pinch detection algorithm based on the fault detection observer estimation is proposed for an anti-pinch window control system. In designing a residual generator, the proposed fault detection algorithm makes use of the pinch torque rate information by establishing the mathematical model of DC, considered as a fault un...

Numerous neurological diseases are accompanied by atrophy of the intrinsic muscles of the hand. Muscle strength testing of these muscles is frequently used for clinical decision making. Traditionally, these strength measurements have focused on manual muscle testing (MMT) or on grip and pinch strength dynamometry. We have developed a hand-held dynamometer, the Rotterdam Intrinsic Hand Myometer ...

We study the power-law scaling behavior and pinch-off morphology of two-dimensional bubble rafts under tension. As a function of pulling speed, we observe two distinct pinch-off morphologies that have been observed in other fluid systems: long threads (LT) and double-cone (DC). At any given pulling speed, there is a nonzero probability of observing LT or DC, with the probability of observing LT...

BACKGROUND PINCH proteins are 5 LIM domain-only adaptor proteins that function as key components of the integrin signaling pathway and play crucial roles in multiple cellular processes. Two PINCH proteins, PINCH1 and PINCH2, have been described in mammals and share high homology. Both PINCH1 and PINCH2 are ubiquitously expressed in most tissues and organs, including myocardium. Cardiac-specific...

The generalization of the pinch technique beyond one loop is presented. It is shown that the crucial physical principles of gauge-invariance, unitarity, and gauge-fixing-parameter independence are instrumental for accomplishing this task, and is explained how the aforementioned requirements single out at two loops exactly the same algorithm which has been used to define the pinch technique at o...

PURPOSE Individuals with spinal cord injuries resulting in tetraplegia may receive tendon transfer surgery to restore grasp and pinch function. These procedures often involve rerouting the brachioradialis (Br) and the extensor carpi radialis longus tendons volar to the flexion-extension axis of the wrist, leaving the extensor carpi radialis brevis (ECRB) muscle to provide wrist extension streng...