With increasing amounts of data describing 3D geometry at scales small and large, shape analysis is becoming increasingly important in fields ranging from computer graphics to robotics to computational biology. While a great deal of research exists on local shape analysis, less work has been done on global shape analysis. This thesis aims to advance global shape analysis in three directions: sy...

This chapter presents a method for ontology construction and its application in developing ontology in the domain of natural gas pipeline operations. Both the method as well as the application ontology developed, contribute to the infrastructure of Semantic Web that provides semantic foundation for supporting information processing by autonomous software agents. This chapter presents the proces...

The Library of Integrated Network-based Cellular Signatures (LINCS) L1000 big data provide gene expression profiles induced by over 10 000 compounds, shRNAs, and kinase inhibitors using the L1000 platform. We developed csNMF, a systematic compound signature discovery pipeline covering from raw L1000 data processing to drug screening and mechanism generation. The csNMF pipeline demonstrated bett...

MOTIVATION We present a pipeline for the pre-processing, quality assessment, read distribution and methylation estimation for methylated DNA immunoprecipitation (MeDIP)-sequence datasets. This is the first MeDIP-seq-specific analytic pipeline that starts at the output of the sequencers. This pipeline will reduce the data analysis load on staff and allows the easy and straightforward analysis of...

High-rate core-to-core communication is critical for efficient pipeline-parallel software architectures. This paper presents the FastForward system, a software-only lowoverhead high-rate queue implementation for pipeline parallelism on multicore architectures. FastForward uses an architecturally-tuned domain-specific adaptation of concurrent lock-free queues to provide low-latency and lowoverhe...

This article presents a method for ontology construction and its application in developing an ontology in the domain of natural gas pipeline operations. Both the method, as well as the application ontology developed, contribute to the infrastructure of Semantic Web that provides semantic foundation for supporting information processing by autonomous software agents. This article presents the pr...

A phase-sensitive optical time domain reflectometer (Φ-OTDR) can be used for pipeline security. However, the sensing distance (less than 20 km) of traditional Φ-OTDR is too short for the needs of typical oil and gas pipeline monitoring applications (30-50 km). A simple structure Φ-OTDR system utilizing long pulse, balanced amplified detector and heterodyne detection is proposed in this paper an...

SAS v9 provides many new features of interest to users with large data sets. Many of the commonly used procedures are multi-treaded. This allows users to harness the full power of multi-processor architectures to enhance the efficiency of some tasks. In addition, SAS/Connect allows users to spawn multiple independent processes to execute custom parallel processing solutions. SAS/Connect also en...