In the title compound, C(25)H(26)ClN, the piperidine ring has a chair conformation with all ring substituents in equatorial positions. The dihedral angle formed between the chloro-benzene ring and the flanking phenyl rings are 74.91 (18) and 47.86 (17)°. The chloro substituent is anti to the piperidine N atom. In the crystal, centrosymmetrically related mol-ecules aggregate via π-π inter-action...

A heterocyclic compound is a cyclic compound that has atoms of at least two different elements as members of its ring(s). The counterparts of heterocyclic compounds are homo cyclic compounds although heterocyclic compounds may be inorganic, most contain at least one carbon. Since in organic chemistry non-carbons usually are considered to replace carbon atoms, they are called heteroatoms, meanin...

A new piperidine amino acid, 2,4,5-piperidinetricarboxylic acid (11) was isolated from the poisonous mushroom, Clitocybe acromelalga. The structure determination and its biogenetic potential are discussed.

In the mol-ecule of the title compound, C(17)H(24)N(2)O(6), the dihedral angle between the four coplanar atoms of the piperidine ring and the benzene ring is 39.2 (1)°.

In the title compound, C(20)H(24)FNO(3)S, the piperidine ring adopts a chair conformation. The dihedral angle between the aromatic rings is 47.01 (17)°.

The six-membered ring of the title compound, C(11)H(16)NO, has a distorted envelope conformation. The piperidine N atom deviates by 0.128 (1) Å from the plane through its three neighbouring atoms. In the crystal structure, mol-ecules are connected by inter-molecular C(ethyn-yl)-H⋯O contacts to form chains extending in the [10] direction.

In the title compound, C(8)H(12)N(2)O, the piperidine ring exhibits a chair conformation and its least-squares plane (all atoms) makes a dihedral angle of 32.88 (12)° with the propane-nitrile unit (r.m.s. deviation = 0.001 Å). In the crystal, mol-ecules are linked by C-H⋯O hydrogen bonds, forming chains along [001].

An L-shaped conformation is found in the title mol-ecule, C(20)H(20)F(6)N(2)O, the C-C-C-C torsion angle linking the two fused-ring systems being -92.80 (19)°. The oxazole ring adopts an envelope conformation [the N atom lies 0.579 (2) Å out of the plane defined by the remaining atoms], and the piperidine ring has a chair conformation. Supra-molecular chains are found in the crystal structure t...

Translation inhibitors of the 3,5-diamino-piperidine series act as aminoglycoside mimetics that inhibit bacterial growth. Here we show antibacterial SAR in the presence and absence of serum with a particular focus toward Pseudomonas aeruginosa.

Herein we report the obtaining of 1-(3,4-dihydroquinolin-1(2H)-yl)-2- (4-isobutylphenyl)propan-1-one and its characterization. The newly obtained hybrid derivatives (hybrids ibuprofen with 1,2,3,4-tetrahydroisoquinoline, piperidine) were screened for their in vitro antioxidant, antitryptic, inhibition albumin denaturation activity. lipophilicity was established using both reversed-phase thin la...