There has been significant growth and advancement since, the last few decades in use of platelet its derivatives dentistry predominantly oral surgery periodontology. Very little is known about same orthodontics. emerging literature on platelets Platelets being reservoir cytokines factors plays a crucial role various regenerative processes. This review attempts to summarise concerning applicatio...

The effect of short- and long-term feeding with L-carnitine, L-acetyl carnitine and L-propionyl carnitine on the production of eicosanoids from in vitro stimulated carrageenan-induced rat peritoneal macrophages was investigated. Both young (4 weeks) and old (18 months) rats were used. A lower number of cells was isolated from the peritonea of treated than control young rats after 4 d feeding, b...

The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that regulates cell growth, proliferation, metabolism, and cell survival, and plays those roles by forming two functionally distinct multiprotein complexes: mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2). Deregulation of the mTOR pathway has been found in different cancers, including multiple myeloma. Agents acting on mT...

Our knowledge regarding chemical structure and properties of heparin its derivatives, including biological in blood plasma, on the cell surface while interacting with receptors, has been progressively growing. New insights are followed by expansion therapeutic opportunities indications for use heparins. There prerequisites creation new generation drugs modified that reduce a bleeding risk appli...

Our aim was to evaluate oxidative stress in diabetes mellitus by the measurement of biophysical parameters (changes) of hemoglobin macromolecule and some biochemical parameters on two groups of diabetic patients, non-insulin dependent diabetes mellitus (NIDDM), and insulindependent diabetes mellitus (IDDM). This study has been conducted on 45 NIDDM, 30 IDDM, compared to 20 healthy subjects. Blo...

A novel series of succinyl derivatives of three curcuminoids were synthesized as potential prodrugs. Symmetrical (curcumin and bisdesmethoxycurcumin) and unsymmetrical (desmethoxycurcumin) curcuminoids were prepared through aldol condensation of 2,4-pentanedione with different benzaldehydes. Esterification of these compounds with a methyl or ethyl ester of succinyl chloride gave the correspondi...

Radionuclidic techniques may provide assessment of glomerular filtration rate (GFR) effective renal plasma flow (ERPF) or individual renal function. Several agents were available for determination of these parameters such as ¹³¹I-OIH (O-iodohippurate) and different derivatives of DADS (Diamidodisulfur). OIH has the disadvantage of imparting a relatively high absorbed radiation dose to the...

W e study the variations of the received frequencies (Complex Doppler effect) from a source moving uniformly in a homogeneous isotropic plasma and emitting a uniform EM plane wave with amplitude E0 , as a function of coe/Eo where coe is the plasma frequency. The ratio of the velocity U of the source over the group velocity UgT of the transmitted wave is then calculated from the slope of the Dop...

Most used in physiotherapy physical factors has an electromagnetic nature. Initially, the therapeutic effect of electromagnetic radiation in a wide range of frequencies associated with activation of metabolic processes in the exposed tissues. The most highly-absorbing ultra high frequency (UHF) energy of tissues are the blood, lymph, parenchymatous tissue, muscles. One of the most important fac...

The effect of the electrical charge on the intestinal absorption of a protein was studied in normal adult rats. Chicken egg lysozyme (Lyz), a basic protein with a molecular weight of 14,300, was selected and several techniques for chemical modification were applied. Then the intestinal absorption of Lyz derivatives was evaluated by measuring the radioactivity in plasma and tissues, after the ad...