Background . Multiple myeloma complicated by extramedullary plasmacytoma is an unfavorable variant of the disease. It remains unknown what triggers tumor transformation. The review presents literature data on pathogenesis disease, as well a clinical example comprehensive study substrate. Aim To molecular and biological characteristics substrate bone marrow using various research methods. Materi...

We report a case of solitary plasmacytoma of the clivus in a 55 year old male.

solitary plasmocytoma is rarely located in the cranial vault. we report one case of solitary plasmacytoma of the skull and discuss the clinical features and treatment of this uncommon tumor in the light of the published cases. a 46-year-old moroccan male, without previous history consulted for a swelling in medial frontal and paramedian region. on clinical examination the clinical examination r...

Solitary plasmacytoma of bone is a rare malignant tumor mostly involving the axial skeleton. The tumor occurs in middle- aged or elderly people (mean age: 55 years) and has a high risk of progression to multiple myeloma. Radiotherapy is the preferred treatment for this disease. We report a case of recurrent solitary plasmacytoma of the fourth lumbar vertebra in a 35-year-old male. The patient s...