Abstract Background Central nervous system involvement is extremely rare in eosinophilic granulomatosis with polyangiitis, and associated very poor prognosis. A high index of suspicion needed to diagnose this entity initiate prompt treatment for life-threatening condition. Case presentation 71-year-old man was admitted our hospital lower limb weakness, loss vision the left eye diplopia four wee...

Abstract
 Background/Aims: In this study, the results of patients who had orthotopic heart transplantation (OHT) in acute rejection admitted to our clinic with decompensated failure and could not undergo endomyocardial biopsy (EMB) were evaluated.
 
 Methods: The study included 27 underwent OHT between December 1998 November 2021, causing during follow-up, EMB administered IV pul...

Stiff-person syndrome (SPS) is a disabling central nervous system disorder characterized by muscle stiffness, rigidity, and superimposed painful spasms affecting axial and proximal limb muscles. Electromyography shows continuous motor unit activity in axial muscles. There is strong evidence of an autoimmune pathogenesis for SPS. High levels of antibodies against the 65-kD isoform of glutamic ac...

*Corresponding author: Mansoor Karimifar, Department of Rheumatology, Isfahan University of Medical Sciences, Isfahan, Iran. E-mail: [email protected] Systemic lupus erythematosus (SLE) is a systemic disease that can lead to involvement of many organs such as bone marrow, blood vessels, skin, heart, kidneys and central nervous system (1). Thrombotic thrombocytopenic purpura (TTP) is c...

Active systemic lupus erythematosus in a 32-year-old Chinese woman was successfully controlled by plasmapheresis and steroids. However, occult visceral leishmaniasis was uncovered during therapy and responded to appropriate treatment.