Cancer cell invasion and metastasis require the concerted action of several proteases that degrade extracellular matrix proteins and basement membranes. Recent reports suggest the plasminogen activator system plays a critical role in pancreatic cancer biology. In the present study, we determined the contribution of the plasminogen activator system to pancreatic cancer cell invasion in vitro. Mo...

Cancer cell invasion and metastasis require the concerted action of several proteases that degrade extracellular matrix proteins and basement membranes. Recent reports suggest the plasminogen activator system plays a critical role in pancreatic cancer biology. In the present study, we determined the contribution of the plasminogen activator system to pancreatic cancer cell invasion in vitro. Mo...

Background: A fine balance exists between the early treatment of a potentially lethal prostate disease and possible complications from indolent disease. Prostate-specific antigen (PSA) is an indicator progression used in clinical staging cancer (PCa). Given arsenal methods available, some intrusive, not, there future for biochemical staging? As presence stage are influenced by multiple factors,...