BACKGROUND Point-of-care CD4 tests at HIV diagnosis could improve linkage to care in resource-limited settings. Our objective is to evaluate the clinical and economic impact of point-of-care CD4 tests compared to laboratory-based tests in Mozambique. METHODS AND FINDINGS We use a validated model of HIV testing, linkage, and treatment (CEPAC-International) to examine two strategies of immunolo...

Upper-ocean fluxes of particulate organic carbon (POC) and biogenic silica (bSi) are calculated from four US JGOFS cruises along 1701W using a thorium-234 based approach. Both POC and bSi fluxes exhibit large variability vs. latitude during the seasonal progression of diatom dominated blooms. POC fluxes at 100m of up to 50mmolCm 2 d 1 are found late in the bloom, and farthest south near the Ros...

[1] Particulate organic carbon (POC) export fluxes were estimated in the shelf-slope region of the Chukchi Sea using measurements of Th U disequilibria and the POC/Th ratio in large (>53-mm) particles. These export fluxes were used in conjunction with rates of primary productivity and benthic carbon respiration to construct a POC budget for this shelf-slope region. Samples were collected along ...

AIMS To examine the effects of processes of change (POC) on forward stage movement directly, indirectly through decisional balance and temptation, and total effects as a test of the key hypothesis of the Transtheoretical Model (TTM). DESIGN Prospective cohort study. SETTING United Kingdom. PARTICIPANTS A total of 1160 adolescents aged 13-14 years who were current or former smokers at base...

BACKGROUND Ischemic preconditioning (IPC) and postconditioning (POC) are well documented to trigger cardioprotection against ischemia/reperfusion (I/R) injury, but the effect oftheir both co-application remains unclear in human heart. The present study sought to assessthe co-application of IPC and POC on fragments of human myocardium in vitro. METHODS Muscular trabeculae of the human right at...

The Open Mobile Alliance (OMA) is defining the Push-to-talk over Cellular (PoC) service where SIP is the protocol used to establish half-duplex media sessions across different participants, to send instant messages, etc. This document defines a SIP event package to support publication, subscription, and notification of additional capabilities required by the PoC service. This SIP event package ...

BACKGROUND The core objective of any point-of-care (POC) testing program is to ensure that testing will result in an actionable management decision (e.g. referral, confirmatory test, treatment), within the same clinical encounter (e.g. POC continuum). This can but does not have to involve rapid tests. Most studies on POC testing focus on one specific test and disease in a particular healthcare ...

CONTEXT The association between combined oral contraceptives (OC) and the risk of myocardial infarction (MI) has been intensively studied, and conclusions are controversial. While progestogen-only contraceptives (POC) are commonly used worldwide, their impact on cardiovascular diseases is poorly investigated and remains unclear. OBJECTIVE We carried out a meta-analysis based on EMBASE- and ME...

INTRODUCTION Both polyester composite (POC) and polytetrafluoroethylene (PTFE) mesh are commonly used for laparoscopic ventral hernia repair. However, sparse information exists comparing perioperative and long-term outcome by mesh repair. METHODS A prospective database was utilized to identify 116 consecutive patients who underwent laparoscopic ventral hernia repair at The Mount Sinai Hospit...

BACKGROUND N-terminal prohormone of brain natriuretic peptide (NT-proBNP) concentrations may be increased in cats with various cardiac disorders. The point-of-care (POC) ELISA assay uses the same biologic reagents as the quantitative NT-proBNP ELISA. Previous studies have evaluated the sensitivity and specificity of the POC ELISA in cats with cardiac disease. OBJECTIVES To prospectively evalu...