نتایج جستجو برای: podophyllotoxin

تعداد نتایج: 437  

Journal: :IOP Conference Series: Earth and Environmental Science 2021

2017
M. H. Yashavarddhan Sandeep K. Shukla Pankaj Chaudhary Nitya N. Srivastava Jayadev Joshi Mrutyunjay Suar Manju L. Gupta

Drug discovery field has tremendously progressed during last few decades, however, an effective radiation countermeasure agent for the safe administration to the victims of radiation exposure is still unavailable. This multi-model study is aimed at elucidating the mechanistic aspects of a novel podophyllotoxin and rutin combination (henceforth referred as G-003M) in the hematopoietic radioprote...

2013
Juan Li Hua Sun Lu Jin Wei Cao Jin Zhang Chong-Yi Guo Ke Ding Cheng Luo Wen-Cai Ye Ren-Wang Jiang

Podophyllotoxin (POD) is a lignan-type toxin existing in many herbs used in folk medicine. Until now, no effective strategy is available for the management of POD intoxication. This study aims to determine the protective effects of flavonoids (quercetin and kaempferol) on POD-induced toxicity. In Vero cells, both flavonoids protected POD-induced cytotoxicity by recovering alleviating G2/M arrest,...

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