Kratom (Mitragyna speciosa) is a plant consumed throughout the world for its stimulant effects and as an opioid substitute (1). It is typically brewed into a tea, chewed, smoked, or ingested in capsules (2). It is also known as Thang, Kakuam, Thom, Ketum, and Biak (3). The Drug Enforcement Administration includes kratom on its Drugs of Concern list (substances that are not currently regulated b...

background: the current study aimed to test the hypothesis: is suicide predictable? and try to classify the predictive factors in multiple suicide attempts. methods: a cross-sectional study was administered to 223 multiple attempters, women who came to a medical poison centre after a suicide attempt. the participants were young, poor, and single. a logistic regression analiysis was used to clas...

Hihi (Notiomystis cincta) were reintroduced to Mokoia Island, Lake Rotorua, New Zealand, in September 1994, and two years later there was an aerial drop of brodifacoum cereal pellets aimed to eradicate mice (Mus musculus). Using Program MARK, we analyzed data from resighting surveys to assess whether hihi had lower than normal survival in the 6-week interval following the drop. The resighting d...

ed from Public Health Dispatch, MMWR, Morbidity and Mortality Weekly Report, Vol. ٥٠ Oct ١٢, ٢٠٠١ CONTRIBUTION OF ENVIRONMENTAL FACTORS TO THE RISK OF MALE INFERTILITY In creasing number of reports suggest that chemical and physical agents in the environment introduced and spread by human activity may affect male fertility in humans. The relationship between exposure to environmental agents and...

Limitations of retrospective analyses R.S. Hoffman Poison centers provide poison prevention and safety information, professional education, and assistance with the diagnosis and treatment of poisoning. These invaluable efforts are linked to medically and legally mandated record keeping, which entails continuous and archived collection of data over time. Surrounded by gigabytes of information re...

Topo II poisons, which target topoisomerase II (topo II) to generate enzyme mediated DNA damage, have been commonly used for anti-cancer treatment. While clinical evidence demonstrate a capability of topo II poisons in inducing apoptosis in cancer cells, accumulating evidence also show that topo II poison treatment frequently results in cell cycle arrest in cancer cells, which was associated wi...

Ovo izvje{}e Centra za kontrolu otrovanja Instituta za medicinska istra`ivanja i medicinu rada nastavak je izvje{}a objavljenih u prethodnim brojevima ovog ~asopisa (Varnai VM et al. Arh Hig Rada Toksikol 2006;57(2):245-249, Macan J et al. Arh Hig Rada Toksikol 2006;57(3):359-363, Varnai VM et al. Arh Hig Rada Toksikol 2006;57(4):477-482; Varnai VM et al. Arh Hig Rada Toksikol 2007;58(1):73-78)...

Literature regarding acute human toxicity of thiopurines is limited to a handful of case reports. Our objectives were to describe all cases of overdose with thiopurines reported to the Swiss Toxicological Information Centre between 1995-2013. A retrospective analysis was performed to determine circumstances, magnitude, management and outcome of overdose with these substances. A total of 40 case...

INTRODUCTION Poisoning is an increasingly important cause of injury in the United States. In 2009 poison centers received 2,479,355 exposure reports, underscoring the role of poison centers in intentional and unintentional injury prevention. Antiretroviral (ARV) agents are commonly prescribed drugs known to cause toxicity, yet the frequency of these incidents is unknown. The objectives of this ...