نتایج جستجو برای: polyethyleneglycol 200

تعداد نتایج: 139290  

2015
Liang Li Boyang Shang Lei Hu Rongguang Shao Yongsu Zhen

In this study, N-terminal site-specific mono-PEGylation of the recombinant lidamycin apoprotein (rLDP) of lidamycin (LDM) was prepared using a polyethyleneglycol (PEG) derivative (M w 20 kDa) through a reactive terminal aldehyde group under weak acidic conditions (pH 5.5). The biochemical properties of mPEG-rLDP-AE, an enediyne-integrated conjugate, were analyzed by SDS-PAGE, RP-HPLC, SEC-HPLC ...

Journal: :Lab on a chip 2008
C Holtze A C Rowat J J Agresti J B Hutchison F E Angilè C H J Schmitz S Köster H Duan K J Humphry R A Scanga J S Johnson D Pisignano D A Weitz

Drops of water-in-fluorocarbon emulsions have great potential for compartmentalizing both in vitro and in vivo biological systems; however, surfactants to stabilize such emulsions are scarce. Here we present a novel class of fluorosurfactants that we synthesize by coupling oligomeric perfluorinated polyethers (PFPE) with polyethyleneglycol (PEG). We demonstrate that these block copolymer surfac...

Journal: :Glycobiology 2012
M Eugenia Giorgi Laura Ratier Rosalía Agusti Alberto C C Frasch Rosa M de Lederkremer

The trans-sialidase of Trypanosoma cruzi (TcTS) catalyzes the transfer of sialic acid from host glycoconjugates to terminal β-galactopyranosides in the mucins of the parasite. During infection, the enzyme is actively shed by the parasite to the bloodstream inducing hematological alterations. Lactitol prevents cell apoptosis caused by the TcTS, although it is rapidly eliminated from the circulat...

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