Aberrant mitochondrial energy transfer underlies prevalent chronic health conditions, including cancer, cardiovascular, and neurodegenerative diseases. Mitochondrial transplantation represents an innovative strategy aimed at restoring favorable metabolic phenotypes in cells with dysfunctional energy metabolism. While promising, significant barriers to in vivo translation of this approach abound...

Polymer relies on its special properties, which is an effective means to enhance oil recovery. But the composition of its produced liquid is very complex, especially emulsifying phenomenon severely constrains the process oil-water separation at a later stage. At present technical means of demulsification taken by both home and abroad oilfield mainly include physics, chemistry and other methods....

Transparent polymer nanocomposites with high refractive index were prepared by grafting polymer chains onto anatase TiO2 nanoparticles via a combination of phosphate ligand engineering and alkyneazide ‘‘click’’ chemistry. Highly crystalline TiO2 nanoparticles with 5 nm diameter were synthesized by a solvothermal method and used as high refractive index filler. The synthesized phosphate-azide li...

A four-step soft lithographic process based on micro-contact printing of organic monolayers, hyperbranched polymer grafting, and subsequent polymer functionalization results in polymer/n-alkanethiol patterns that direct the growth and migration of mammalian cells. The functional units on these surfaces are three-dimensional cell "corrals" that have walls 52+/-2 nm in height and lateral dimensio...

Recent advances in the field of self-assembly have led to the development of a plethora of new technologies derived from soft lithography that enable alternative ways of fabricating thin films with twoand three-dimensional patterns on material surfaces. Techniques involving the patterning of thicker polymer layers grafted to the substrate have been developed, based on selectively decorating the...

The stability of weak polyelectrolytes end grafted to a planar surface has been studied with a molecular theory. The effective quality of the solvent is found to depend on the interplay between polymer grafting density, acid-base equilibrium, and salt concentration. Our results reveal that increasing salt concentration results in a thermodynamically more stable layer. This reverse salt effect i...

Surface-active polymers that display nonfouling properties and carry binding groups that can adsorb onto different substrates are highly desirable. We present a postmodification protocol of an active-ester-containing polymer that allows the creation of such a versatile platform. Poly(pentafluorophenyl acrylate) has been postmodified with a fixed grafting ratio of a nonfouling function (mPEG) an...

In this work the selectivity of crosslinked organic solvent stable PBI membranes is tuned by varying molar ratio two grafting agents: a long flexible polymer modifier (Elastamine RE-1-1000, 1000 g mol-1) and small molecule (2-methoxyethylamine, 75 mol-1). Grafting exclusively with chain provided membrane molecular weight cut-off (MWCO) 2000 mol-1 in acetonitrile. Increasing proportion reaction ...

In this study, an end-functionalized graft copolymer, thiol-terminated poly(2-hydroxyethyl methacrylate-g-ethylene glycol) or SH-poly(HEMA-g-EG), was synthesized by the atom transfer radical polymerization (ATRP) method and then characterized by 1H nuclear magnetic resonance (NMR), gel permeation chromatography (GPC), and light scattering (LS). The polymer was covalently end-grafted to an Au su...