BACKGROUND Polymorphonuclear neutrophils are involved in the development of myocardial injury during ischaemia and reperfusion. Coronary angioplasty has been shown to result in neutrophil activation. This may be a result of contact with ligands expressed by endothelial cells or response to soluble stimuli released from ischaemic tissue into the plasma or both. OBJECTIVE To investigate plasma ...

Sperm vitrification has been recently developed, but fertility trials have not performed yet in equine species. In this study, a new warming technique for vitrified donkey semen was developed and the uterine inflammatory response were compared to conventional freezing. Experiment 1, sperm straws warmed 3 ml of extender or water bath at: 37 °C/30 s; 43 °C/10 60 °C/5 s. motility, plasma acrosome ...

In this issue of Blood, Wang et al. uncover a key role for programmed death ligand 1 (PD-L1), which delays neutrophil apoptosis at the inflammatory site through activation PI3K-AKT survival pathway 1. Polymorphonuclear neutrophils (PMN) are most abundant circulating leukocytes, constituting 60 to 70% white blood cells. PMN terminally differentiated and have short life span, but essential innate...