Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) was overexpressed and purified from Escherichia coli. Mouse monoclonal antibodies (mAbs) were prepared that react with EBNA1. Eleven high affinity mAbs were recovered. Nine mAbs are isotype IgG (all subisotype IgG(1)) and two mAbs are isotype IgM. All mAbs react strongly with EBNA1 in an ELISA assay while only one mAb (designated 1EB6) fails to...

Aspergillus nidulans wild-type and the extreme carbon catabolite derepressed mutant creAd-30 were characterized with respect to enzyme activities, metabolite concentrations and polyol pools all related to glycolysis, after growth on D-glucose. In the creAd-30 strain the enzymes hexokinase and fructose-6-phosphate reductase showed a two- and threefold increase in activity, respectively, whereas ...

Esterification reactions of some polyols and diols were investigated in the presence of SnO2 and nano-SnO2 and the results were compared with the catalyst-free conditions. High conversions were obtained for most of the reactions in the presence of SnO2 and nano-SnO2 which shows the high catalytic activity of SnO2 and nano-SnO2</sub...

Maria Ahrén, Linnéa Selegård, Fredrik Söderlind, Mathieu Linares, Joanna Kauczor, Patrick Norman, Per-Olov Käll and Kajsa Uvdal, A simple polyol-free synthesis route to Gd2O3 nanoparticles for MRI applications: an experimental and theoretical study, 2012, Journal of nanoparticle research, (14), 8. http://dx.doi.org/10.1007/s11051-012-1006-2 Copyright: Springer Verlag (Germany) http://www.spring...

Two highly convergent syntheses of a fully protected C1-C19 polyol subunit of the brasilinolide family of immunosuppressive macrolides are described, exploiting boron-mediated 1,5-anti aldol couplings to form the C8-C9 and C13-C14 bonds.

With diabetes reaching epidemic proportions, there is an urgent need for reliable treatment strategies for microvascular (retinopathy, neuropathy, and nephropathy) and macrovascular (coronary heart disease and stroke) diabetes complications. The role of diabetic hyperglycemia in the development of complications has been extensively studied and a number of biochemical pathways activated by hyper...

Abstract By partially substituting 1,3,5-tris-(2-hydroxyethyl) cyanuric acid for glycerol as the polyol, new modified alkyd resins having a wide range of oil length and hydroxyl content were produced. FT-IR, 1 H NMR, iodine values, other characterization techniques used to confirm chemical compositions resins. The drying qualities synthesized significantly enhanced by adding greater quantity fr...