TO THE EDITOR: To Drs. Bonnema and colleagues, thank you for your comments on our recent article in AJP-Endocrinology and Metabolism (4). Indeed, for subjects not used to these polyols, 50 g of xylitol and 75 g of erythritol as a single bolus given within 2 min seems rather high. From a nutritional point of view the applied doses makes sense, at least in adapted subjects. This would then, for i...