PURPOSE To investigate and compare the surface roughness and morphology of posterior stromal lenticules created with a femtosecond laser using various pulse energies to that obtained with a mechanical microkeratome. METHODS A 150 kHz femtosecond laser platform (IntraLase iFS; Abbott Medical Optics) was programmed to create an 8.5-mm-diameter posterior stromal lenticule in 12 human corneal tis...

For more than 100 years, eye scientists and clinicians have recognized that there is a difference between the refractive and anterior corneal astigmatism of the human eye. Javal postulated an approximately linear relationship between corneal astigmatism and refractive astigmatism, which became known as Javal’s rule: refractive astigmatism 1⁄4 1.25 (keratometric astigmatism) 0.50 90. For most ey...

BACKGROUND/PURPOSE Keratoconus is the most common primary corneal ectatic disease and has considerable importance in public health. Corneal collagen crosslinking (CXL) is a procedure to mitigate progression of keratoconus and reduce demand for corneal transplantation. The aim of this study was to evaluate the effect of CXL on corneal topographic and uncorrected distance visual acuity (UDVA) by ...

PURPOSE To assess the repeatability of corneal wavefront aberrations derived from Pentacam (Oculus) corneal topography. SETTING Flinders Eye Centre, Flinders Medical Centre, Bedford Park, South Australia, Australia. METHODS Forty-five normal participants and 10 participants with keratoconus were tested. Intraobserver and interobserver repeatability was determined using 4 observers within an...

PURPOSE To describe the effect of the corneal asphericity and toricity on the map patterns and best fit sphere (BFS) characteristics in elevation topography. METHODS The corneal surface was modeled as a biconic surface of principal radii and asphericity values of r1 and r2 and Q1 and Q2, respectively. The apex of the biconic surface corresponded to the origin of a polar coordinates system. Mi...

PURPOSE We compared corneal backscatter estimated from a Scheimpflug camera with backscatter estimated from a clinical confocal microscope across a wide range of corneal haze. METHODS A total of 59 corneas from 35 patients with a range of severity of Fuchs' endothelial corneal dystrophy and 15 corneas from 9 normal participants were examined using a Scheimpflug camera (Pentacam) and a confoca...

OBJECTIVE: It was aimed to evaluate the changes observed in anterior segment parameters patients with keratoconus using Pentacam device according severity of disease and compare determined results those obtained from healthy individuals.MATERIAL AND METHODS: The data by for 104 eyes 52 120 60 individuals were retrospectively evaluated. Demographic features patients, corneal curvature posterior ...

Introduction To evaluate the expression patterns of cytokeratin (K) 12, 13, and 19 in normal epithelium of the human ocular surface to determine whether K13 could be used as a marker for conjunctival epithelium. Methods: Total RNA was isolated from the human conjunctiva and central cornea. Those transcripts that had threefolds or higher expression levels in the conjunctiva than the cornea wer...

Posterior polymorphous dystrophy is a rare corneal dystrophy, usually detected by chance. This case series describes the morphologic features in the three different types of posterior polymorphous dystrophy using confocal microscopy.