نتایج جستجو برای: potassium release
تعداد نتایج: 287107 فیلتر نتایج به سال:
Large-conductance calcium-activated potassium (BK) channels regulate the electric properties and neurotransmitter release in excitable cells. Its auxiliary β2 subunits not only enhance gating, but also confer inactivation via a short-lived preinactivated state. However, the mechanism of enhancement and preinactivation of BK channels by β2 remains elusive. Using our newly developed methods, we d...
Contributions of Kv7-mediated Potassium Current to Suband 1 Suprathreshold Responses of Rat Layer II/III Neocortical Pyramidal 2 Neurons. 3 4 5 Guan D1, Higgs MH2, Horton, LR1, Spain WJ2, and Foehring RC1. 6 7 1Department of Anatomy and Neurobiology 8 University of Tennessee 9 855 Monroe Avenue 10 Memphis, TN 38163 11 12 2VA Puget Sound Health Care System 13 MS: 151 14 1660 S Columbian Way 15 N...
Diversity in the expression of K(+) channels among neurons allows a wide range of excitability, growth, and functional regulation. Ether-à-go-go (EAG), a voltage-gated K(+) channel, was first characterized in Drosophila mutants by spontaneous firing in nerve terminals and enhanced neurotransmitter release. Although diverse functions have been ascribed to this protein, its role within neurons re...
Voltage-gated ion channels are important mediators of physiological functions in the central nervous system. The cyclic activation of these channels influences neurotransmitter release, neuron excitability, gene transcription, and plasticity, providing distinct brain areas with unique physiological and pharmacological response. A growing body of data has implicated ion channels in the susceptib...
Neurons express a variety of plasma-membrane potassium channels that play important roles in regulating neuronal excitability and synaptic transmission, but also contain mitochondrial ATP-sensitive potassium channels, the functions of which are unknown. Studies of cardiac cells suggest that similar mitochondrial ATP-sensitive potassium channels are involved in the process of ischemic preconditi...
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