BACKGROUND Leptin (Lep) is known for its involvement in the regulation of reproductive functions. It is important for uterine receptivity, implantation, placental growth and maternal energy homeostasis in several species, but Lep's function in the pregnant dog has not been investigated. METHODS Pregnant bitches were ovariohysterectomized at pre-implantation, post-implantation, mid-gestation a...

Objective: Present study investigated the effects of parsley extract on pregnant rat kidneys which have undergone clinical abortion using prostaglandins. The renal protective effect of parsley extract was evaluated in pregnant rats which had an abortion. Parsley was used due to its antioxidant properties. Materials and Methods:  Fifty-four female rats were divided in 9 groups of 6: control preg...

OBJECTIVE The aim of this case series was to assess the impact of auditory rehabilitation with cochlear implantation on the cognitive function of elderly patients over time. DESIGN This is a longitudinal case series of prospective data assessing neurocognitive function and speech perception in an elderly cohort pre- and post-implantation. SETTING University cochlear implant center. PARTIC...

Penile prosthesis surgery has become the standard treatment for patients with erectile dysfunction refractory to medical management. Refinements in the both the surgical technique and device manufacturing have made this a safe and reliable treatment with excellent patient satisfaction. In this review, we will overview the basic medical and pre-operative considerations for patients undergoing pe...

Methods This prospective trial was conducted at 50 U.S. centers. Patients were eligible if they met MADIT-II (Multicenter Automatic Defibrillator Implantation Trial II) indications for device implant. All patients underwent MTWA testing followed by ICD implantation, with pre-specified programming to minimize the likelihood of therapies for non–life-threatening VTE. Minimum follow-up was 2 years...

Pre-surgery evaluation, indications for cochlear implantation and expectations in terms of post-operative functional results remain challenging topics in pre-lingually deaf adults. Our study has the purpose of determining the benefits of Single Photon Emission Tomography (SPECT) assessment in pre-surgical evaluation of pre-lingually deaf adults who are candidates for cochlear implantation. In 7...

Abstract Introduction Originally considered as the “forgotten valve disease”, tricuspid regurgitation (TR) has recently been shown to correlate with consistent morbidity and mortality, suggesting need for a deeper understanding of its natural course. Direct injury from Cardiac Implantable Electrical Device (CIED) leads is one most common causes primary TR, prevalence up 40%. The aim present pro...

Correspondence to: Mario Abbud Filho. Uro Institute. Rua Voluntarios de São Paulo, no 3826, São José do Rio Preto, SP, Brazil. CEP: 15015-200. E-mail: [email protected] We often face the dilemma of accepting or rejecting extended criteria or “high risk” kidneys and having to make a quick decision, usually in the middle of the night and without much time to think. Histological assessment by ...

Graphical Abstract Highlights d Reversion or derivation of hESCs in 5iLAF results in SSEA4-negative cells d SSEA4-negative hESCs show gene expression consistent with naive pluripotency d Naive hESCs show lost ''memory'' of gamete and blastocyst methylation d Imprinting is lost in naive hESCs In Brief Pastor and colleagues show that reversion of primed hESCs in 5iLAF, or derivation of hESCs in 5...

background: magnetized water has made many improvements in industry, agriculture and medicine. however its utilization in medicine still remains controversial. objective:  in this study we aimed to investigate the effects of magnetized water on height of epithelial cells in pre-implantation stage endometrium and fallopian tube and number of corpus lutea in female mice. materials and methods:  e...