Introduction: Precancerous lesions, conditions, and early-stage oral cancer cannot be sufficiently identified solely through visual inspection may prone to inadvertently disregarded. Distinguishing between cancer, precancerous benign tumors can pose a challenge due the striking resemblance in their characteristics. Using surgical biopsy as diagnostic modality is widely regarded gold standard me...

Aims. Worldwide, cervical cancer is the fifth most deadly cancer in women, but screening prevents cancer by detecting precancerous lesions. The purpose of this study is to present the treatment profile for precancerous lesions of the uterine cervix, according to demographic data. Methods. An annual retrospective study was conducted in two public primary health care centres in Greece. The total ...

Nicotine, a tumor promoter in tobacco, can increase Peroxiredoxin (Prx1) and nicotinic acetylcholine receptors (nAChRs) in oral squamous cell carcinoma (OSCC). In the present study, we investigate the effects of nicotine in oral precancerous lesions focusing on apoptosis and nAChR/Prx1 signaling. We detected expression of Prx1, α3nAChR, α7nAChR, phosphorylation of mitogen-activated protein kina...

Although recent studies have suggested that tooth loss is positively related to the risk of gastric non-cardia cancer, the underlying oral health conditions potentially responsible for the association remain unknown. We investigated whether clinical and behavioral measures of oral health are associated with the risk of gastric precancerous lesions. We conducted a cross-sectional study of 131 pa...

several lesions (inflammatory, neoplastic and congenital) can involve in the skull base. the role of imaging is to detect the location and extension of lesion, determine mass and mass like lesions, differentiate benign from malignant tumors, detect invasion to adjacent structures and make decision in surgical planning. skull base divides to anterior, middle and posterior cranial fossa and some ...

Esophageal squamous cell carcinoma is a common fatal cancer, and Shanxi province, a region in north-central China, has some of the highest esophageal cancer rates in the world. Chromosomal regions with frequent allelic loss may point to major susceptibility genes that will assist us in understanding the molecular events involved in esophageal carcinogenesis and may serve as the basis for the de...