Oral tolerance is a physiological immune mechanism, which controls the outcome of deleterious hypersensitivity reactions to environmental antigens absorbed through the gastrointestinal tract, and maintains homeostasis. Using a mouse model of oral tolerance of delayed type hypersensitivity to contact allergens, i.e. haptens, we have examined the mechanisms involved in the induction of oral toler...

Aspergillus oryzae is an industrially relevant organism for the secretory production of heterologous enzymes, especially amylases. The activities potential amylases, however, cannot be quantified directly from supernatant due to high background activity native α-amylase. This caused by gene products amyA, amyB, and amyC. In this study, in vitro CRISPR/Cas9 system was established A. delete these...

Nowadays, an area-based approach seems to be common for urban policies in Western Europe. Policies are directed towards spatially defined areas in order to be more efficient in solving problems in cities. Yet, besides solving problems in the targeted area, an area-based approach has an in-built danger: it might lead to a displacement of problems. This so-called spatial knock-on effect is an eff...

This paper presents an experimental investigation into the detection of excessive diesel knock using acoustic emission (AE) signals. Three different dual-fuel diesel engine operating regimes were induced into a compression-ignition (diesel) engine operating on both straight diesel fuel and two different mixtures of fumigated ethanol and diesel. The experimentally induced engine operating regime...

Deficiency in the monoamine degradation enzyme monoamine oxidase A (MAOA) or prenatal exposure to the monoamine uptake inhibitor cocaine alters behavior in humans and rodents, but the mechanisms are unclear. In MAOA knock-out mice, inhibiting serotonin synthesis during development can prevent abnormal segregation of axons in the retinogeniculate and somatosensory thalamocortical systems. To inv...

Homogeneous Charge Compression Ignition (HCCI) combustion is a pioneer method of combustion in which pre-mixed fuel and oxidizer (typically air) are compressed to the point of auto-ignition. HCCI engines can operate with most alternative fuels, especially, dimethyl ether (DME) which has been tested as a possible diesel fuel due to its simultaneously low NOx and PM emissions. In this paper a ...

homogeneous charge compression ignition (hcci) combustion is a pioneer method of combustion in which pre-mixed fuel and oxidizer (typically air) are compressed to the point of auto-ignition. hcci engines can operate with most alternative fuels, especially, dimethyl ether (dme) which has been tested as a possible diesel fuel due to its simultaneously low nox and pm emissions. in this paper a sin...

background: progressions in science and technology have generated several methods for delaying preterm delivery and abortion; therefore, discovering an easy, non-invasive, practical, and non-expensive predictive factor can help us to perform preventive methods in healthy pregnant women, without any risk factors. objective: to indicate an appropriate index for predicting abortion in early pregna...

introduction: acinetobacter baumannii is associated with hospital-acquired infections. outer membrane protein a of a.baumannii (abompa) is a well-characterized virulence factor which has important roles in pathogenesis of this bacterium. methods: based on our pcr-sequencing of ompa gene in the clinical isolates, abompa protein can be categorized into two types, named here type-1 and type-2. we ...