Endothelial tip cells are leading cells at the tips of vascular sprouts coordinating multiple processes during angiogenesis. In the developing retina, tip cells play a tightly controlled, timely role in angiogenesis. In contrast, excessive numbers of tip cells are a characteristic of the chaotic pathological blood vessels in proliferative retinopathies. Tip cells control adjacent endothelial ce...

BACKGROUND Human metapneumovirus (HMPV) is a recently discovered respiratory pathogen of the family Paramyxoviridae, the same family as that of respiratory syncytial virus (RSV). Premature children are at high risk of severe RSV infections, however, it is unclear whether HMPV infection is more severe in hospitalized children with a history of severe prematurity. METHODS We conducted a retrosp...

OBJECTIVES To perform a bibliometric analysis of theses and dissertations on prematurity in the Capes database from 1987 to 2009. METHODS This is a descriptive study that used the bibliometric approach for the production of indicators of scientific production. Operationally, the methodology was developed in four steps: 1) construction of the theoretical framework; 2) data collection sourced f...

ern medicine. In USA, prematurity accounts for more than 12% of all live newborn infants, a 20% increase from 1990. The same trend has been observed in most high income countries, including Eastern Europe countries, Japan, Australia and Canada, even when rates are lower. As an example of the extent of this problem, USA currently ranks 131 out of 184 countries worldwide in the prematurity rate r...

Introduction: Retinopathy of prematurity is a bilateral dysfunction abnormal retinal vascularization in preterm infants, especially those with very low birth weight. The consequences range from normal vision to blindness. In recent years, the survival rate for extreme group patients has increased 8% 35% middle-income countries, as well its early identification damage and institution appropriate...