In the prepubertal male, Sertoli cells are the most active testicular cell population. Without stimulation tests, prepubertal hypogonadism can only be evidenced if Sertoli cell function is assessed. Anti-müllerian hormone (AMH) is a distinctive marker of the prepubertal Sertoli cell. Serum AMH is high from fetal life until puberty. In postnatal life, AMH testicular production is stimulated by F...

OBJECTIVE Our aim was to reveal a change in the prevalence of metabolic syndrome (MS) in the province of Konya in five years. METHODS We studied 202 obese children and adolescents (body mass index >95th percentile) aged between 7 and 18 years. The diagnosis of impaired glucose tolerance, type 2 diabetes mellitus (T2DM), and MS were defined according to the modified World Health Organization c...

The aim of this study was to evaluate whether fixed blood lactate reference values of 2.5 and 4.0 mmol.1(-1) corresponded to the equivalent intensity of exercise in prepubertal and teenage boys, and men. Twenty six prepubertal boys (mean(sd) age) 11.1(0.4) years), 26 teenage boys (mean(sd) age 14.1(0.3) years), and 23 men (mean(sd) age 22.4(2.7) years) gave informed consent to participate in th...

A series of experiments evaluated development of porcine zygotes microinjected with DNA in three culture media and two incubation temperatures, from postpubertal and prepubertal donors, and between zygotes injected with DNA into the pronucleus and the cytoplasm. Zygotes recovered from 36 postpubertal gilts in Exp. 1 were injected and cultured in modified NCSU-23, modified NCSU-37, and CZB media...

PURPOSE The anatomic origin for prepubertal vowel acoustic differences between male and female subjects remains unknown. The purpose of this study is to examine developmental sex differences in vocal tract (VT) length and its oral and pharyngeal portions. METHOD Nine VT variables were measured from 605 imaging studies (magnetic resonance imaging and computed tomography) of subjects between bi...

Both the magnitude and the duration of the hormonal stress response change dramatically during neonatal development and aging as well as with prior experience with a stressor. However, surprisingly little is known with regard to how pubertal maturation and experience with stress interact to affect hypothalamic-pituitary-adrenal axis responsiveness. Because adolescence is a period of neurodevelo...

The present experiments investigated the effects of pubertal maturation and photoperiod on the size of brain regions that mediate mating behavior in the male Syrian hamster. We hypothesized that the low levels of reproductive behavior exhibited by prepubertal and photoinhibited males would be correlated with morphological changes in the neural circuit that mediates mating behavior. We found tha...

[Objective] Discrimination between hypogonadotropic hypogonadism (HH) and constitutional delayed puberty (DP) is difficult in prepubertal patients. We retrospectively analyzed the usefulness of the gonadotropin-releasing hormone (GnRH) test using time-resolved fluoroimmunoassay (TR-FIA) for the measurement of gonadotropins and the human chorionic gonadotropin (hCG) test to discriminate between ...

INTRODUCTION Nasal obstruction secondary to pathological enlargement of inferior nasal turbinates contributes to sleep-disordered breathing (SBD) in prepubertal children, but treatments designed to address turbinate enlargement are often not performed. The aims of these studies are: (1) to appreciate the contribution to SDB of untreated enlarged nasal turbinates in prepubertal children; and (2)...

Skeletal muscle mass in prepubertal Asian children has not been examined previously. The aims of this study were to test the hypotheses that 1) prepubertal Asians have less appendicular skeletal muscle (ASM) mass compared with African-Americans and Caucasians, and 2) ASM is less in prepubertal Asian girls compared with Asian boys. ASM was estimated by using dual-energy X-ray absorptiometry in h...