BACKGROUND Myocardial dysfunction occurs in a variety of fetal disorders. Findings from adult cardiology, where n-terminal pro-B-type natriuretic peptide (nt-proBNP) is an established biomarker of left ventricular dysfunction have been extended to fetal life. Since fetal blood sampling is technically challenging we investigated amniotic fluid nt-proBNP for its suitability to diagnose fetal myoc...

Background: Preterm delivery (PTD; < 37 gestational weeks), is one of the greatest unsolved obstetrical problems worldwide. As much as 80% of the perinatal mortality and 50% of the long-term neurological handicaps are associated with PTD. Spontaneous preterm birth (SPTD), i.e. preterm labor (PTL) or preterm prelabor rupture of membranes (PPROM) is responsible for 55% of PTD. Clinical and experi...

For decades GBS has been the most common cause of early-onset neonatal infection. Ascending route infection with Group B Streptococcus bacteria increases risk preterm premature rupture membranes, fetus infection, sepsis, birth, and meningitis in infants. C-Reactive Protein is a sensitive marker systemic inflammation where an increase CRP can also be triggered by Objective this study to determin...

BACKGROUND: In the presence of meconium in amniotic fluid, childbirth is usually classified as a high-risk group, which leads to an expansion indications for operative delivery. Also literature there are increase frequency birth child state asphyxia, with premature rupture fluid.&#x0D; AIM: The aim this study determine significance influence color fluid and duration anhydrous period on asphyxia...

OBJECTIVE The purpose of this study was to evaluate the effectiveness of antibiotic treatment of bacterial vaginosis in pregnancy to reduce preterm delivery. STUDY DESIGN We performed a meta-analysis of published, English-language, randomized, placebo-controlled clinical trials of antibiotic treatment of bacterial vaginosis in pregnant women with intact amniotic membranes at <37 weeks of gest...

THE ROLE OF ALARMINS, INVARIANT NKT CELLS AND SENESCENCE IN THEPATHOPHYSIOLOGY OF STERILE INTRA-AMNIOTIC INFLAMMATIONbyOLESYA PLAZYOAugust 2016Advisor: Nardhy Gomez-Lopez, Ph.D.Major: Physiology (Reproductive Sciences Concentration)Degree: Doctor of PhilosophyPreterm birth is defined as the delivery of a live baby prior to the 37th week ofgestation. It is...

BACKGROUND Histologic chorio-deciduitis and chorio-deciduo-amnionitis (amnionitis) in extra-placental membranes are known to represent the early and advanced stages of ascending intra-uterine infection. However, there are no data in humans about the time required for chorio-deciduitis to develop and for chorio-deciduitis without amnionitis to progress to chorio-deciduitis with amnionitis, and t...

amniotic fluid volume (afv) is one of the important parameters in the assessment of fetal well-being. the ability of ultrasound measurements to represent the actual afv is unproven. this study was undertaken to compare correlation of conventional amniotic fluid index (afi) and radial amniotic fluid index (rafi) as a new method with actual fluid volume on phantom. as an experimental study, 10 to...

Objective-The purpose of this study was to find out prevalence ,risk factors, mode of delivery, & perinatal out come in Meconium stained amniotic fluid (MSAF) during delivery At term pregnancy.Study design-this retrospective study was conducted in MGMC&RI,puducherry with womens at 37-42 wks of gestation those were meconium stained amniotic fluid during labour & delivery.Different maternal outco...