OBJECTIVES To longitudinally assess bone mineral content (BMC), bone mineral density (BMD), and whole-body lean mass obtained through bone densitometry by dual-energy X-ray absorptiometry (DXA) in preterm newborns (PTNs) and compare them with full-term newborns (FTNs) from birth to 6 months of corrected postnatal age. METHODS A total of 28 adequate for gestational age (AGA) newborns were stud...

Introduction: Minimally invasive surgery is normally used in children but is not so common in newborns, especially those with very low birth weight, as a consequence of an immature cardiopulmonary system and technical difficulties. Case Description: A preterm female with very low birth weight (1.4 kg), born in the 32nd week of gestation with a prenatal diagnosis of abdominal cyst, presented wit...

Background and Objective: Congenital heart disease (CHD) is the most form of cardiovascular disease in children. CHD have different presentations, from defects that progress asymptomatically to those with significant symptoms and high mortality. This study was performed to highlight the importance of signs and symptoms to diagnosis of CHD neonates. Materials & Methods: This descriptive analyt...

Exosomes are secreted nanovesicles that are able to transfer RNA and proteins to target cells. The emerging role of mesenchymal stem cell (MSC) exosomes as promoters of aerobic ATP synthesis restoration in damaged cells, prompted us to assess whether they contain an extramitochondrial aerobic respiration capacity. Exosomes were isolated from culture medium of human MSCs from umbilical cord of ≥...

Background: Newborns’ health is one of the important indexes in health services. The aim of this study was to assess the relationship between newborns' sex and rate of admission at NICU and mode of delivery. Materials and Methods: This descriptive and analytic study was confirmed on 492 newborn that was admitted to NICU of Rouhani Hospital of Babol University from March 2012 to 2013. Data ...

Preterm newborns are challenged by an excessive oxidative burden, as a result of several perinatal stimuli, as intrauterine infections, resuscitation, mechanical ventilation, and postnatal complications, in the presence of immature antioxidant capacities. "Oxygen radical disease of neonatology" comprises a wide range of conditions sharing a common pathway of pathogenesis and includes bronchopul...

Data regarding epidemiological aspects, antiretroviral drug safety, and outcomes of HIV-infected pregnant women and their newborns are limited in Argentina. We underwent a retrospective analysis of registries of HIV-infected pregnant women assisted at Helios Salud, Buenos Aires, Argentina (1997-2006). Variables associated with preterm delivery and neonatal complications were analyzed by univari...

In preterm infants, RDS is primarily caused by deficiency of pulmonary surfactant in an immature lung. For the past 50 years, related research and experiments with regards to surfactant replacement therapy have been encouraging and inspiring. Numerous trials have been conducted to demonstrate that surfactant plays an important role in the management of respiratory distress syndrome in preterm b...

BACKGROUND Despite the clinical relevance of necrotizing enterocolitis (NEC), it remains difficult to predict which preterm infants are more likely to develop NEC. Contrary to the neonatal risk factors for the development of NEC, little information is available regarding maternal (prenatal) risk factors. We aimed to identify maternal risk factors associated with the subsequent development of NE...

OBJECTIVE To investigate whether fetal growth restriction (FGR) diagnosis, based on pathological prenatal fetal Doppler velocimetry, is associated with bronchopulmonary dysplasia (BPD) independently of being small for gestational age (SGA) per se at birth among very preterm infants. DESIGN Prospective, observational study. FGR was defined as failing fetal growth in utero and fetal Doppler vel...