Primary spinal primitive neuroectodermal tumors (PNETs) are uncommon malignancies that are increasingly reported in the literature. Spinal PNETs, like their cranial counterparts, are aggressive tumors and patients with these tumors typically have short survival times despite maximal surgery, chemotherapy, and radiation. Because no standard management guidelines exist for treating these tumors, ...

Primitive neuroectodermal tumors (PNETs) located in the spine are extremely rare, and information concerning these tumors in the medical literature is limited to single case reports. This pictorial essay presents the clinical, pathological, and imaging characteristics of PNET of the spine.

Osteosarcoma refers to a bone tumor and the term was introduced by John Abernathy in 1804 referring fleshy growth [1]. In 2009, Ottaviane G. et al reported that osteosarcoma is an aggressive malignancy arises from primitive transformed cells of mesenchymal origin produces malignant osteoid, which are most common representation primary cancer [2,3].

Peripheral primitive neuroectodermal tumors - also known as Ewing sarcomas - are a rare type of malignant tumor the histology of which characteristically reveals the presence of small round cells. Typically, t(11;22) translocation is observed. We describe the case of a 45-year-old man with a subcutaneous peripheral primitive neuroectodermal tumor in which the t(11;22) translocation was detected...

Primitive neuroectodermal tumor (PNET) is anundifferentiated neoplasm arising from the germinal matrix of the primitive neural tube. It is predominantly an infratentorial tumor of childhood. Adult supratentorial PNETs are less common and extraneural metastasis are extremely unusual. Only five sporadic cases were reported in the international literature.1–6 In this article, we report a rare case...

Primitive neuroectodermal tumor is a small round cell malignancy which rarely involves the orbit. We report a case of a two-year old male child presenting as unilateral eccentric proptosis with extraconal and intraconal mass, diagnosed as primary peripheral primitive neuroectodermal tumor (pPPNET) on histopathology and immunohistochemistry. There is no defined consensus in the management of the...