This paper proposed a stiffness analysis method for a 3-PRS mechanism for welding thick aluminum plate using FSW technology. In the molding process, elastic deformation of lead-screws and links are taken into account. This method is based on the virtual work principle. Through a survey of the commonly used stiffness performance indices, the minimum and maximum eigenvalues of the stiffness matri...

Liver fibrosis, the response to chronic liver injury, results from the activation of mesenchymal cells to fibrogenic myofibroblasts. We have recently shown that two key myofibroblast precursor populations, hepatic stellate cells and portal fibroblasts, undergo activation in culture in response to increasing substrate stiffness. We therefore hypothesized that alterations in liver stiffness prece...

Structural design often includes geometrically nonlinear analysis to reduce structural weight and increase energy efficiency. The full-order finite element model can perform the analysis, but its computational cost is expensive. Therefore, reduced-order models (NLROMs) have been developed costs. non-intrusive NLROM has a lower than other due approximation of internal force by polynomial reduced...