A current focus of biopharmaceutical research and production is seed train process intensification. This allows for intermediate cultivation steps to be avoided or even the direct inoculation a bioreactor with cells from cryovials cryobags. Based on preliminary investigations regarding suitability high cell densities cryopreservation perfusion cultivations as inoculum further cultivations, an u...

This article presents the process of workers' problems with work related musculoskeletal disorders (WMSDs), the introduction of risk assessments (RA) for their prevention, and the consequences of this process in Korea. In 1997, economic crisis caused a rapid increase of massive layoffs, worker dispatch system introduction, job insecurity, and use of irregular workers resulting in work intensifi...

This article reviewed on agricultural intensification from livelihood and environment perspectives in mid-hills of Nepal. Agricultural intensification has provided improved economy, food security, employment opportunities, decision-making, labor division, local institutions and leaderships. But soil degradation has been accelerated along with greenhouse gases emission. Additionally, the potenti...

Despite their key roles in agroecosystems, species diversity of arable plants is being severely reduced by agricultural intensification, although it remains unclear whether functional diversity is affected in a similar way. We analyzed the response of four functional traits of arable plants (specific leaf area, canopy height, seed mass and flowering onset) to agricultural intensification in Med...

Available online xxxx Smallholder livestock keepers represent almost 20% of the world population and steward most of the agricultural land in the tropics. Observed and expected increases in future demand for livestock products in developing countries provide unique opportunities for improving livelihoods and linked to that, improving stewardship of the environment. This cannot be a passive proc...

urban expansion and agriculture intensification are relevant drivers in land degradation (ld)processes in europe due to net loss of land, soil sealing, landscape fragmentation and other negative effects on the environment. this paper explores changes (or “trajectories” of change) in land use and cover (lulc) and their relationship with the consumption of soils in emilia-romagna (northern italy)...

BACKGROUND Comorbidity is often mentioned as interfering with "optimal" treatment decisions in diabetes care. It is suggested that diabetes-related comorbidity will increase adequate treatment, whereas diabetes-unrelated comorbidity may decrease this process of care. We hypothesized that these effects differ according to expected priority of the conditions. METHODS We evaluated the relationsh...