نتایج جستجو برای: prolonged unconjugated hyperbilirubinemia

تعداد نتایج: 92836  

Journal: :Gastroenterology 1997
C N Van der Veere P L Jansen M Sinaasappel R Van der Meer H Van der Sijs J A Rammeloo P Goyens C M Van Nieuwkerk R P Oude Elferink

BACKGROUND & AIMS Calcium phosphate binds unconjugated bilirubin in vitro, and dietary calcium phosphate supplementation reduces the serum bilirubin level in rats with hereditary unconjugated hyperbilirubinemia (Gunn rats). The aim of this study was to evaluate the effect of oral calcium phosphate supplementation on plasma bilirubin levels in patients with Crigler-Najjar disease. METHODS A pl...

Journal: :Journal of neonatal surgery 2016
Jasbir Singh Poonam Dalal Kapil Bhalla Kamal Nain Rattan

Adrenal hemorrhage is quiet uncommon in neonates with reported incidence of 0.2%-0.55% [1]. In neonates, adrenal glands are large in size and have abundant vascular supply, so more prone to hemorrhage. Clinical manifestations may vary from relatively benign as anemia, flank mass, discoloration of scrotum, neonatal jaundice to life threatening addisonian crisis depending upon the extent of hemor...

2004
Liang Lijun Akira Matsunaga Kazuki Kijima Emi Shirahata Hiroko Izumino Kiyoshi Hayasaka

Address for Correspondence:Kiyoshi Hayasaka, Department of Pediatrics, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan We present two patients with idiopathic nephrotic syndrome who showed temporary indirect hyperbilirubinemia during the course of treatment with immunosuppressant drugs and/or steroids. We analyzed the gene of the bilirubin uridine-diphosphate ...

2014
Dilek Konukbay

Background: There is risk of developing bilirubin encephalopathy (kernicterus) in cases in which early diagnosis and treatment of high bilirubin levels are not available. The follow-up and treatment of neonatal indirect hyperbilirubinemia are, therefore, important. Aim: This study was conducted to evaluate the relationship between serum bilirubin levels and the frequency of urination and stooli...

Journal: :Circulation 2012
Tatsuya Maruhashi Junko Soga Noritaka Fujimura Naomi Idei Shinsuke Mikami Yumiko Iwamoto Masato Kajikawa Takeshi Matsumoto Yasuki Kihara Kazuaki Chayama Kensuke Noma Ayumu Nakashima Hirofumi Tomiyama Bonpei Takase Akira Yamashina Yukihito Higashi

BACKGROUND Patients with Gilbert syndrome have mild unconjugated hyperbilirubinemia. It has been shown that bilirubin is an endogenous antioxidant. We evaluated the role of oxidative stress in endothelial function in patients with Gilbert syndrome under normal conditions without cardiovascular risk factors. METHODS AND RESULTS A total of 108 young men with Gilbert syndrome without cardiovascu...

2015
Mehrdad Asgeri

This study examines abnormal LFT (mainly bilirubin) on postoperative day three as a predictor of open cardiac surgery mortality.1 Preoperative hyperbilirubinemia, high right atrial pressure, number of heart valves replaced and high blood transfusion requirements are risk factors predicting postoperative hyperbilirubinemia in 81% of all patients.2 This study strictly excluded high-risk condition...

Journal: :Archives of disease in childhood 2001
W S Lee P J McKiernan S V Beath M A Preece D Baty D A Kelly B Burchell D J Clarke

BACKGROUND Early and accurate diagnosis of Crigler-Najjar syndrome, which causes prolonged unconjugated hyperbilirubinaemia in infancy, is important, as orthotopic liver transplantation is the definitive treatment. AIM To determine whether bilirubin pigment analysis of bile in infants with prolonged unconjugated hyperbilirubinaemia provides useful diagnostic information in the first 3 months ...

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