Some new nitrogen bridge-head pyrido[1,2-b][1,2,4]triazepines incorporating 6methylchromone moiety have been synthesized from the reaction of 1,6-diamino-4-(6methyl-4-oxo-4H-chromen-3-yl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile (4) with some α,γ-bifunctional electrophiles including 2-cyano-3,3-bis(methylthio)acrylonitrile, 2cyano-3,3-bis(methylthio)prop-2-enamide, 5-chloro-3-methyl-1-pheny...

In the title compound, C23H22ClNO4 (systematic name: (RS)-2-(4-chloro-phen-yl)-N-{2-[3-meth-oxy-4-(prop-2-yn-1-yl-oxy)phen-yl]eth-yl}-2-(prop-2-yn-yloxy)acetamide), an amide fungicide, the dihedral angle between the chloro-benzene and benzene rings is 65.36 (6)°. In the crystal, N-H⋯O hydrogen bonds lead to zigzag supra-molecular chains along the c axis (glide symmetry). These are connected int...

The asymmetric unit of the title compound, [Co(NCS)(2)(C(6)H(17)N(3))], consists of one Co(2+) cation, two thio-cyanate anions and one bis-(3-amino-prop-yl)amine ligand, all in general positions. The cobalt cation is coordinated by five N atoms of two terminal N-bonded thio-cyanate anions and one bis-(3-amino-prop-yl)amine ligand, defining a slightly distorted square-pyramidal coordination poly...

must be the field, two copies of the field, the split quaternions, or the split octonions. There is a natural q-version of the composition property that the algebra Oq of quantum octonions is shown to satisfy (see Prop. 4.12 below). We also prove that the quantum octonion algebra Oq satisfies the “q-Principle of Local Triality” (Prop. 3.12). Inside the quantum octonions are two nonisomorphic 4-...

We have studied the expression of the pituitary transcription factors Ptx-1 and Prop-1 in a series of 34 pituitary adenomas fully characterized for in vitro hormone secretion and histological staining. In studies involving mammalian cell lines, the pituitary transcription factor Ptx-1 has been shown to be a pituitary hormone panactivator, whereas more recent studies have shown that it plays an ...

The title compound, C(17)H(17)NO, was prepared by the condensation of cinnamaldehyde with p-phenetidine in ethanol. The prop-2-enyl-idene group exhibits an E configuration at the N=C and C=C double bonds, with C-N-C-C and C-C-C-C torsion angles of -179.9 (3) and -175.9 (3)°, respectively. The prop-2-enyl-idene group is not strictly planar [maximum deviation = 0.054 (4) Å] and forms dihedral ang...

Min introduces the type form (of object-formulae) and the infix constant −→ (for objectimplication). The constant [[ ]] maps form to the predefined type prop of meta-logic propositions. The proposition [[P ]] should be read as “the formula P is true”; we usually distinguish object-level formulae (form) from meta-level formulae (prop). In practice the brackets can be dropped; parser and pretty-p...

The California Stem Cell Research and Cures Act, also called Proposition 71 [5], was a ballot initiative proposed by California voters in 2004 to allocate three billion dollars of state funds for stem cell research over ten years. Endorsed by California scientists and patient-advocates, Prop 71 passed on 2 November 2004, amending the state constitution to make stem cell research a constitutiona...

Mutations of the PROP-1 gene are the most frequent genetic defect in patients with combined pituitary hormone insufficiency. We present the cases of 2 siblings with PROP-1 mutations whom we observed longitudinally. Their initial pituitary MR imaging examinations showed identical findings: an enlarged adenohypophysis, with striking hypointensity on T2-weighted images and slight hyperintensity on...