نتایج جستجو برای: protein interaction network could reveal
تعداد نتایج: 3036235 فیلتر نتایج به سال:
OBJECTIVE Rheumatoid arthritis (RA) is a heterogeneous disease, and traditional Chinese medicine (TCM) can be used to classify RA into different patterns such as cold and hot based on its clinical manifestations. The aim of this study was to investigate potential network-based biomarkers for RA with either a cold or a hot pattern. METHOD Microarray technology was used to reveal gene expressio...
While the genomic revolution has dramatically accelerated the discovery of disease-associated genes, the functional characterization of the corresponding proteins lags behind. Most proteins fulfill their tasks in complexes with other proteins, and analysis of protein-protein interactions (PPIs) can therefore provide insights into protein function. Several methods can be used to generate large-s...
Introduction We have integrated phylogenetic, protein-protein interaction, genetic interaction, and gene expression data to provide a comprehensive and up-to-date description of the topology and properties of the nuclear receptor (NR) dimerization network in humans. We classified and described the different NR protein and association entities in OWL and we used the Protégé platform as a data in...
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