Journal:
:iranian journal of basic medical sciences
0
ningning dang department of dermatology, jinan central hospital affiliated to shandong university, jinan, shandong province, 250013, china
college of life science, shandong normal university, jinan shandong province, 250014, china
shuguang pang department of endocrinology, jinan central hospital affiliated to shandong university, jinan, shandong province, 250013, china
haiyan song department of dermatology, jinan central hospital affiliated to shandong university, jinan, shandong province, 250013, china
liguo an college of life science, shandong normal university, jinan shandong province, 250014, china
xiaoli ma central laboratory, jinan central hospital affiliated to shandong university, jinan, shandong province, 250013, china
objective(s):several investigations have revealed that caspase-14 is responsible for the epidermal differentiation and cornification, as well as the regulation of moisturizing effect. however, the precise regulation mechanism is still not clear. this study was aimed to investigate the expression of caspase-14 in filaggrin-deficient normal human epidermal keratinocytes (nheks) and to explore the...